Metabolomics presents challenges for both the analytical methods used and the data reduction required to interpret the results. No single analytical technique can be used for complete characterisation of the metabolome, and no metabolome has been completely characterised. However, GC-MS provides an established method to analyse the primary metabolome, whereas LC investigates the secondary and tertiary metabolites.

Cost Effective Soil Analysis with the LECO CHN828

Soil is the material where corn grows. This sounds to be a simple sentence, but keep in mind, that a big part our food is directly or indirectly coming from plants that are sown, grown and harvested in agricultural soil. For modern agriculture especially when including environmental concerns, the chemical analysis delivers very important parameters for a complete characterisation of soil. LECO is the specialist for CNS and moisture/ash analysis in soil, as well as for Carbon species analysis like TOC/TIC or according to EN 17505 TOC400, ROC, ROC900 and TIC 900.

The rise of omics has been a hot topic in our group for the past few years – in part because our own expertise aligns somewhat with the needs of these fields. Metabolomics is then particularly challenging for the separation science community, demanding the application of high-end iterations of various techniques, including LC, GC, MS, and NMR. In fact, when it comes to metabolomics, most analytical tools have a “seat at the technique table” – after all, multimodality is the only way to make sense of such high sample complexity.

An Article by Pierre-Hugues Stefanuto, Delphine Zanella, and Jean-François Focant

From cancer to diabetes to the recent rise of COVID-19, we will all likely come face-to-face with a threat to our health. Contemporary medicine has ever-improving tools to identify and combat diseases, but there are gaps – in speed, in invasiveness, in coverage, in access, and in accuracy. Can we do better? And how can we ensure that new approaches provide the same level of diagnostic potential as those currently in service?

Jane Hill, Associate Professor of Engineering, and Billy Boyle, CEO of Owlstone Medical, explain how their research in the area of breath analysis is opening new diagnostic doors.

Carbon / Hydrogen / Nitrogen / Sulfur Analysis. 

With the introduction of the LECO CHN 828 Series another Cornerstone® elemental analyser has been added to the LECO portfolio. The workshops topics are designed to show proceedings in organic elemental CHNS analysis with LECO Instruments. CHNS determination from low sample weights up to 2g with highest precision and accuracy in many organic and inorganic matrices. High throughput and low costs per analysis for a modern laboratory. Further information can be found on our registration page.

Measurement of Chemically and Structurally Transformed Steel

Do you struggle with analyzing the quality and composition of your steel? How easily can you measure the surface hardness or fluctuating carbon concentrations? Are you confident with what your tools are telling you? Learn how LECO has been expanding what is possible when it comes to measuring steel with this free series of webinars.

Find out how the use of Comprehensive Two-Dimensional Gas Chromatography (GC×GC) with Time-of-Flight Mass Spectrometry (TOF-MS) demonstrates excellent matrix-analyte and analyte-analyte separation quality of a high number of target pesticides, at high sensitivity.

The LECO Pegasus BT 4D was used to develop a robust and straightforward quantification workflow adhering to SANTE requirements.

Liberty Powder Metals, United Kingdom

"As a small business the user-friendly interfaces and built-in functionality, such as maintenance reminders and OEM manuals, have helped us to get up to speed with our ON736 and CS744 machines quickly.

The ongoing technical support and adaptability to our application requirements has been second to none."

See What's in Your Food

How efficient is your workflow when it comes to food samples? Are you sure you're seeing everything your sample has to offer? Learn how LECO has been expanding what is possible when it comes to food safety analyses with this free series of webinars.