LECO
Empowering Results
Displaying items by tag: Separation Science
Unveiling the Future of
Non-Targeted Screening
Welcome to LECO, where innovation meets precision, even for unknown sample testing. Our cutting-edge GC×GC and HRT/MMS technologies redefine non-targeted screening, empowering laboratories across all industries. Explore the limitless possibilities as we revolutionise screening techniques for enhanced quality and confidence in results.
"Join us in navigating non-targeted frontiers, where possibilities are limitless, and results are unparalleled.
Choose LECO –
your partner in revolutionising
non-targeted screening."
Explore Our Products
Dive into our comprehensive range of products designed to meet the unique challenges of non-targeted screening. From food safety and environmental analysis to pharmaceutical and petrochemical applications, LECO's advanced instrumentation offers unparalleled insights and efficiencies. Elevate your laboratory's capabilities with our state-of-the-art solutions.
Find further details about LECO's PEGASUS® instruments on our separation science analysis compendium page.
Watch the Webinar - April 5th, 2024
Join us on April 5th for an immersive webinar experience. Discover the latest advancements in non-targeted screening technologies, practical applications, and case studies that showcase the power of LECO's GC×GC and HRT systems. Don't miss this opportunity to stay ahead in the rapidly evolving landscape of substance analysis.
LECO NTS Sympoium 2024
Join us in Manchester, Berlin or Nice and take your chance to be part of this transformative experience.
- May 21 – 22, 2024 Alderley Park, Manchester, UK
- October 28 – 30, 2024 Berlin EATC, GER
- November 19 – 21, 2024 Nice Université Côte d'Azur, Nice, FR
Download Brochures
Get in-depth insights into our product offerings through our informative brochures. Understand how LECO's technology addresses the evolving challenges of identifying emerging contaminants. Equip your laboratory with robust, versatile, and cost-effective non-target screening workflows.
Access Application Notes
Delve into real-world scenarios with our NTS application notes. Gain practical knowledge on how LECO's GC×GC and HRT/MMS technologies provide unmatched results in substance screening. From improved accuracy to increased efficiency, our application notes demonstrate the impact of choosing LECO as your non-targeted screening partner.
In the following, you are going to find a content compendium. You can download them here with a click.
- Comprehensive Evaluation of Scotch Whisky Aroma Profiles Using SPME-GC×GC-TOFMS
- Discovery of Environmental Pollutants at an Electronic Waste Recycling Facility by PEGASUS® GC-HRT+ 4D
- Expand Your PFAS Analysis. Screen for Targets and Identify Unknowns Simultaneously
- Petroleum Forensics: Identifying Biomarkers in Crude Oil
- Analysis of Heavy Fuel Oil Using Multi-Mode Ionization
- Characterization of Extractables from Common Pharmaceutical Packaging Materials with GC×GC and HR-TOFMS
- Workflow for the Assessment of Key Aroma Compounds of Pumpernickel Bread Variations
- The Development of Untargeted Metabolite Profiling Methodology for the Analysis of Type-2 Diabetes Patient Plasma
Why Choose LECO?
Innovative Technologies
GC×GC and HRT/MMS technologies redefine non-targeted screening, offering unmatched precision and efficiency.
Comprehensive Solutions
Address the evolving challenges of substance screening across diverse markets, from identifying emerging contaminants to ensuring food safety.
Cost-Effective Workflows
Enhance your efficiency without compromising on quality. LECO provides cost-effective solutions without sacrificing performance.
Market
Leadership
Position your laboratory at the forefront of non-targeted screening with LECO's capabilities.
If you want to learn more about our products and solutions for non-target screening, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
I use LECO PEGASUS® BT 4D to separate, identify and quantify secondary metabolites of various organisms. The advantages of the GC×GC system in separation of multi-component mixtures allow us to separate and identify a huge number of compounds in every samples. The ability to separate and quantify low levels of target analytes in mixtures simultaneously with the major components presented at a high level of concentration and to separate coeluted compounds is a great advantage of two-dimensional GC in comparison with one-dimensional GC. The user-friendly ChromaTOF software and excellent technical support make LECO a reliable partner for researcher. Since we started working on this equipment, our results have become more accurate and comprehensive, and our research has reached a new level.
In our lab, the GC×GC-MS device installed by LECO has been a game-changer for metabolic profiling, especially in our multiomics study exploring the intricacies of obesity in young adults. Its sensitivity has been crucial in identifying and quantifying metabolites, even at low concentrations, essential for uncovering subtle changes in the metabolome. Our experience with PEGASUS® BT 4D device has been exceptionally positive, significantly due to the exceptional support of the service team, ensuring the smooth operation and optimal performance of our instrument.
We started using the LECO PEGASUS® BT GC-TOF mainly for target analysis of aliphatic hydrocarbons on environmental matrices; over time we had the need to develop a method for the qualitative characterization of hop leaves samples for a research project, the ChromaTOF® deconvolution software allowed the identification of several compounds, in particular different terpenes. The Pegasus BT GC-TOF thus proved to be an excellent system, easy to use, with high sensitivity and reproducibility, able to perform both non target and target analysis.
I started working with the PEGASUS GC-HRT+ 4D back in my student years. As a novice researcher, with no experience working with similar devices and no training, it was not easy at first. However, after years of working with this instrument and when compared with other sophisticated equipment in the field of gas chromatography - high-resolution mass spectrometry, I can confidently say that the ChromaTOF is the most user-friendly software of all those available now. Such a variety of functions, as well as very clear, convenient, and fast operation, combined with high-tech equipment, allows to get very decent results.
Over the past 5 years of using the Pegasus GC-HRT+ 4D, we have been able to conduct many various environmental studies, identifying trace amounts of substances in the cleanest Arctic environmental objects. At the same time, such a powerful combination of two-dimensional gas chromatography with time-of-flight mass spectrometry made it possible to analyze complex matrices, namely peat combustion products, herbal and tobacco cigarette smoke, petroleum and much more.
It is worth noting the work of the support service, which helped us very quickly and efficiently. I would like to thank the engineers for their work, who were on call almost 24/7. There are still many projects and tasks ahead that will undoubtedly be solved with the help of the Pegasus GC-HRT+ 4D.
Unveiling the Future of
Non-Targeted Screening
Welcome to LECO, where innovation meets precision, even for unknown sample testing. Our cutting-edge GC×GC and HRT/MMS technologies redefine non-targeted screening, empowering laboratories across all industries. Explore the limitless possibilities as we revolutionise screening techniques for enhanced quality and confidence in results.
"Join us in navigating non-targeted frontiers, where possibilities are limitless, and results are unparalleled.
Choose LECO –
your partner in revolutionising
non-targeted screening."
Explore Our Products
Dive into our comprehensive range of products designed to meet the unique challenges of non-targeted screening. From food safety and environmental analysis to pharmaceutical and petrochemical applications, LECO's advanced instrumentation offers unparalleled insights and efficiencies. Elevate your laboratory's capabilities with our state-of-the-art solutions.
Find further details about LECO's PEGASUS® instruments on our separation science analysis compendium page.
Watch the Webinar - April 5th, 2024
Join us on April 5th for an immersive webinar experience. Discover the latest advancements in non-targeted screening technologies, practical applications, and case studies that showcase the power of LECO's GC×GC and HRT systems. Don't miss this opportunity to stay ahead in the rapidly evolving landscape of substance analysis.
LECO NTS Sympoium 2024
Join us in Manchester, Berlin or Nice and take your chance to be part of this transformative experience.
- May 21 – 22, 2024 Alderley Park, Manchester, UK
- October 28 – 30, 2024 Berlin EATC, GER
- November 19 – 21, 2024 Nice Université Côte d'Azur, Nice, FR
Download Brochures
Get in-depth insights into our product offerings through our informative brochures. Understand how LECO's technology addresses the evolving challenges of identifying emerging contaminants. Equip your laboratory with robust, versatile, and cost-effective non-target screening workflows.
Access Application Notes
Delve into real-world scenarios with our NTS application notes. Gain practical knowledge on how LECO's GC×GC and HRT/MMS technologies provide unmatched results in substance screening. From improved accuracy to increased efficiency, our application notes demonstrate the impact of choosing LECO as your non-targeted screening partner.
In the following, you are going to find a content compendium. We kindly ask you to submit our form. Afterwards you‘ll get access to all the files.
- Comprehensive Evaluation of Scotch Whisky Aroma Profiles Using SPME-GC×GC-TOFMS
- Discovery of Environmental Pollutants at an Electronic Waste Recycling Facility by PEGASUS® GC-HRT+ 4D
- Expand Your PFAS Analysis. Screen for Targets and Identify Unknowns Simultaneously
- Petroleum Forensics: Identifying Biomarkers in Crude Oil
- Analysis of Heavy Fuel Oil Using Multi-Mode Ionization
- Characterization of Extractables from Common Pharmaceutical Packaging Materials with GC×GC and HR-TOFMS
- Workflow for the Assessment of Key Aroma Compounds of Pumpernickel Bread Variations
- The Development of Untargeted Metabolite Profiling Methodology for the Analysis of Type-2 Diabetes Patient Plasma
Why Choose LECO?
Innovative Technologies
GC×GC and HRT/MMS technologies redefine non-targeted screening, offering unmatched precision and efficiency.
Comprehensive Solutions
Address the evolving challenges of substance screening across diverse markets, from identifying emerging contaminants to ensuring food safety.
Cost-Effective Workflows
Enhance your efficiency without compromising on quality. LECO provides cost-effective solutions without sacrificing performance.
Market
Leadership
Position your laboratory at the forefront of non-targeted screening with LECO's capabilities.
If you want to learn more about our products and solutions for non-target screening, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Explore the Fascinating World of Separation Science
The very first GC-MS was a GC-TOFMS which was built in 1947. The information it provided was much too large to record, and it was not until the mid-1990s when LECO introduced the first fast GC-TOFMS, that GC-TOFMS became a useable tool for researchers and analysts. Followed a few years later by LECO’s introduction of the first GC×GC-TOFMS.
Today, LECO’s Separation Science products are recognised across the globe as leading advanced technology innovations in TOFMS Mass Spectrometry and Comprehensive two-dimensional Chromatography.
PEGASUS® BT GC-TOFMS
GC Time-Of-Flight Mass Spectrometer
Today‘s laboratories are being asked for more everyday – more samples run, more data acquired, more chemical information processed, and more results achieved – all in less time, for less money. ...
The Pegasus BT allows you to achieve all you need from a single sample run, while powerful and user-friendly ChromaTOF® software processes your data and removes the guesswork involved with analyte identification, quantitation, and reporting. The Pegasus BT gives users more uptime, better data, and an increase in overall productivity and efficiency.
A time-of-flight mass spectrometer (TOFMS) is ideal for discovering new compounds in your sample, quantifying targeted compounds in complex samples, and increasing throughput with fast chromatography.
► Download the free whitepaper and brochure
PEGASUS® BT 4D GC×GC-TOFMS
GC×GC Time-Of-Flight Mass Spectrometer
The Pegasus BT 4D offers enhanced sensitivity by coupling our benchtop Pegasus BT with a high-performance GC×GC modulation system. This combination gives the Pegasus BT 4D the ability to interrogate challenging samples ...
... where the best sensitivity is needed. Unique and powerful software and hardware features simplify quantitation, while also dramatically making GC×GC easy-to-use and understand. Our thermal modulation system, the QuadJet™, is recognised as the gold standard in GC×GC modulation, providing the highest sensitivity available on the market - ideal for analysing the most complex samples.
One of the main advantages of LECO’s GC×GC-TOFMS is its ability to provide vastly improved peak capacity and resolution than traditional GC-MS systems. It also offers comprehensive information about the sample by separating compounds based on two different properties (volatility and polarity). Combining GC×GC with TOFMS is an ultimate solution for the analysis of complex samples.
► Download the free brochure
PEGASUS® GC-HRT+
High Resolution Time-Of-Flight Mass Spectrometer
Now with even more sensitivity than ever before, the Pegasus GC-HRT+ is the perfect tool for meeting the challenges of today’s highly complex analytical demands. ...
This high-resolution mass spectrometer features industry leading mass accuracy, full mass range acquisition with exceptional speed, full mass range acquisition with exceptional speed, isotopic abundance and mass resolution, all available in a single injection.
Folded Flight Path® (FFP®) technology and a novel data acquisition system enables simultaneous resolutions of over 50,000 FWHM, mass accuracies less than 1 ppm, and acquisition rates up to 200 spectra/second, without the need to adjust tuning or parameters. Thus, facilitating rich analyte finding and high-confidence analyte identification.
► Download the free brochure
PEGASUS® GC-HRT+ 4D
HR GC×GC Time-Of-Flight Mass Spectrometer
The Pegasus GC-HRT+ 4D combines the highest performance GC×GC and TOFMS tools on the market with High Resolution Deconvolution® (HRD®). Ideal for the most complex samples, ...
... users are able to find more analytes than ever before and confidently identify unknown components.
The Pegasus GC-HRT+ 4D takes advantage of four dimensions of separation and resolution:
- 1st dimension chromatographic resolution
- 2nd dimension chromatographic resolution
- High mass resolution and exceptional mass accuracy
- High Resolution Deconvolution (HRD) from the leaders in deconvolution
ChromaTOF brand software, designed specifically for HRT+ instrumentation and GC×GC support, adds advanced qualitative and quantitative capabilities to an all-in-one user-friendly data system.
► Download the free brochure
Examples of LECO Separation Science Applications
Petroleum
Comprehensive Two-Dimensional Gas Chromatography (GC×GC) has proven to be an extremely valuable analytical technique for the petroleum industry due to its ability to substantially increase the chromatographic peak capacity beyond that of traditional single-dimension gas chromatography. Pairing GC×GC with Time-of Flight Mass Spectrometry (TOFMS) provides unsurpassed characterization capabilities due to the separation power of GC×GC and the ability of TOFMS to provide rich data.
Food Testing
The characterization and safety testing of food and food constitutions can be extremely challenging depending on the complexity and the matrix. The LECO GC×GC TOFMS technology provides a highly powerful separation and remarkable identification allowing for improved workflows. More insights thanks to the advanced technology in combination with LECO’s ChromaTOF® brand software deconvolution algorithm and advanced data analysis tool will improve your Food Quality & Safety Testing and Food R&D. Here we demonstrate the aroma analsyis of two types of coffee and coffee packaging and filter leachates.
Perfume and Cosmetics
LECO‘s GC×GC-TOFMS is a valuable asset in the production of cosmetics and perfumes that align with Islamic principles. It can be used to identify the ingredients and detect any prohibited substances such as alcohol or non-halal animal-derived ingredients.
Environmental Analysis
Microplastics are an emerging pollutant which are widely distributed in the environment. Understanding the impact of their growing prevalence on the environment and human health is an important field of research. LECO‘s GC×GC-TOFMS can be used to monitor environmental pollution and air and water quality thus aiding to enforce regulations and ensure the preservation of our environment.
Metabolomics
LECO’s key advantage is the ability to identify and discover more metabolites than other similar technologies. Our speed of full-scan acquisition is unrivaled, and when combined with the power of LECO’s ChromaTOF® brand software deconvolution algorithm, allows an unprecedented characterisation of the biological systems under study. Our instrumentation has been validated by the industry‘s most demanding researchers.
Extractables and Leachables
The characterization of extractable and leachable components from a wide range of materials is an important area of research. Information about extractable and leachable components from packaging and delivery devices for pharmaceutical products is a particular area of growing interest. Analytical testing results on this topic are part of many regulatory submission requirements to the FDA. ...
USP 1663 provides guidance on extractables testing and a variety of analytical approaches can meet compliance. High resolution MS is often considered necessary for identification of unknowns, and sample complexity and low-level detection continue to challenge these analyses. Here, we demonstrate a workflow that uses comprehensive two-dimensional gas chromatography (GC×GC) with HR-TOFMS to help address these challenges.
► App Note | Characterizing Extractables by GC×GC & HR-TOFMS
FAQ – Separation Science
Answer:
Gas chromatography separates components in a mixture by utilizing a thin silica tube coated with a stationary phase. The components, carried by a gas (the mobile phase), move at different speeds based on their affinities for the stationary phase. This differential migration leads to the separation of the components, allowing for their individual analysis and identification.
Alternative response:
- Gas chromatography is a technique for separating a mixture of volatile analytes
- The analytes are transported by a mobile phase (the carrier gas)
- Become distributed between the mobile phase and a stationary phase
- The Stationary Phase is attached to the inside of a very fine column
- Phases are typically characterised by their polarity
- A polar analyte will be retained by polar column for longer than a non-polar analyte
- and vica versa
Answer:
LECO uses Agilent 8890 chromatography. The gas chromatograph includes the following features:
- Compatibility and perfect integration with the mass spectrometer
- Automatic regulation of gas flows
- Agilent supported inlets: Split/Splitless (SSL), Multimode (MMI), Programmable temperature Vaporizer (PTV) etc.
- Programmable oven, up to 450 °C
- Chromatograph compatible with Fast-GC
- The GC is completely controlled by and integrated into LECO’s ChromaTOF software
Answer:
The LECO mass spectrometer is connected to the GC via a heated transfer line. The LECO GC-TOF allows you to have a 'full range' acquisition, without compromise, then a targeted and/or non-targeted data exploitation depending on what you want to do.
It consists of an EI (Electronic Impact) source, a 70 cm flight tube, a reflectron and a detector. Vacuum is provided by an internal turbomolecular pump connected to an external secondary pump.
Answer:
The mass range of the Pegasus BT is from 10 to 1500 m/z. All masses are collected all the time, unlike quadrupole instruments that collect a single mass at a time (quadrupole scanning mode is single ion monitoring, SIM, quickly scanning across the mass range).
Answer:
GC×GC-TOFMS can detect discrepancies in the composition of food products, helping to expose fraudulent claims of Halal certification and ensure consumer confidence in authentic Halal products.
Answer:
By examining the chemical composition of inks and pigments, GC×GC-TOFMS provides insights into the materials used in Islamic calligraphy and manuscripts, aiding in their preservation and authentication. An example of similar work can be read in this publication on analysing the paints used by Leonardo Da Vinci.
Answer:
LECO’s GC×GC-TOFMS system utilizes two columns with different separation mechanisms, providing enhanced chromatographic resolution for the analysis of complex mixtures. In one dimension the analytes are separated by polarity, or according to boiling point. An additional dimension separates according to an alternative property, of which there are many. This results in a 3D image – the two dimensions of separation and the abundance of the analytes in the third dimension.
Answer:
LECO's StayClean® ion source originates in the requirement for a fast source to match the speed of the TOFMS. Accomplished by reducing ion to ion interactions, such as with the walls of the source. The source was thus designed without walls – so there is nothing to clean. Massively reduced downtimes, especially for complex matrices and more reproducible results.
Answer:
Yes! With superior separation power and precision, LECO’s GC×GC-TOFMS system can uncover hidden details and confidently identify components, even in the most intricate mixtures:
- Increases detectability
- Removes analytes from matrix interference
- Separates co-elluting peaks
- Creates cleaner peaks, which match closer with libraries
- Creates structured chromatograms thus further improving identification confidence
Answer:
The cryogenic Quad Jet modulator consistently delivers reproducible quantitative results not only within the lab but also between labs worldwide. This is achieved because:
- There are two cold jets. So, eluent from the primary column does not flow into the secondary column by mistake
- The distance between cold zones is identical in every system worldwide, unlike other systems that require manual adjustment and intervention
- The modulation is completely computer controlled. This along with the 2 separate cold zones, allows for variable modulation periods in the same analysis, vastly improving separation across the chromatogram
- In the same way the primary column is temperature controlled in the primary oven, the secondary column is also independently controlled, allowing for total control of the chromatogram along the entire column setup
These four features not only improve separation and control, they are also unique to the LECO QuadJet.
Answer:
By combining comprehensive two-dimensional gas chromatography (GC×GC) with high-speed, high-sensitivity time-of-flight mass spectrometry (TOFMS), LECO's GC×GC-TOFMS can separate and identify the complex mixtures of flavours and fragrances in food samples with detail and precision.
Answer:
Yes! LECO’s GC×GC-TOFMS is an excellent tool for non-intentionally added substances (NIAS) analysis in food safety. It allows for the comprehensive analysis of complex food samples, ensuring the detection and identification of potential contaminants and unwanted substances. For example, LECO’s MOSH/MOAH solution is widely recognised as the most comprehensive and rigorous analyser for mineral oil contamination in food stuffs.
Answer:
LECO’s GC×GC technology utilizes two stages of separation, significantly increasing resolution and analysis power compared to traditional gas chromatography. This allows for the detailed separation and identification of complex mixtures with unparalleled precision.
Answer:
LECO’s TOFMS technology offers excellent sensitivity, speed, and resolution in mass spectrometry. By fragmenting and ionizing analyte molecules and separating the fragments based on their mass-to-charge ratio, LECO's TOFMS enables highly accurate identification and detection of compounds in samples. The system not only records to a computer at high speed, it detects at a rate of 32,000 Hz thus producing a very high level of accuracy.
Answer:
GC×GC-TOFMS enables the analysis of dietary supplements for the presence of non-compliant ingredients, such as animal-derived gelatine, ensuring that the products meet the strict requirements of Halal certification.
Answer:
GC×GC-TOFMS is a valuable tool for monitoring air and soil quality near Islamic sacred sites, identifying pollutants that may pose a risk to their preservation and guiding conservation efforts. As an example, Imperial College London have utilised a LECO Pegasus BT 4D to identify microplastics in the air of London. You can read about it here.
Answer:
LECO’s GC×GC-TOFMS system utilizes Time-of-Flight Mass Spectrometry (TOFMS), which provides high-speed detection of ionized compounds based on their mass-to-charge ratio.
Answer:
LECO provides software for data analysis, enabling compound identification, quantification, and other types of analysis based on the mass spectra obtained from the TOFMS.
Answer:
LECO’s StayClean ion source, a standard feature in every Pegasus BT GC-TOFMS and GC×GC-TOFMS system, flushes neutrals and contaminants continuously. This virtually eliminates the need for routine maintenance, allowing you to spend less time on upkeep and more time on your research.
Answer:
Sample handling is crucial in GC-MS analysis. LECO employs advanced sample handling robots called Autosamplers that can handle samples in three dimensions of space. These robots ensure precise and consistent sample preparation, ranging from simple liquid injections to complex processes like chemical reactions, extractions, and accurate dilutions.
Answer:
The first GC-MS was a GC-TOFMS developed in the 1950s. However, the technique was too powerful for data recording at the time. In the mid-1990s the first GC-TOFMS capable of recording the data for processing was developed by LECO. This breakthrough in fast GC-TOFMS technology allowed researchers and analysts to utilize the capabilities of GC-TOFMS for their analytical needs.
Answer:
By combining two-dimensional separation, robust ionization, and high-speed TOFMS detection, and patented deconvolution algorithms LECO's GC×GC-TOFMS system offers a powerful solution for analysing complex mixtures with enhanced resolution, sensitivity, and separation power.
Answer:
By analysing the chemical composition of materials used in ancient Islamic artifacts, GC×GC-TOFMS assists in determining their authenticity, providing valuable insights into historical and cultural heritage. The chemical composition of such artifacts are extremely complex so utilising multidimensional chromatography techniques with high speed TOFMS, a chemical profile can be created. Furthermore, LECO’s post processing software packages, ChromaTOF Tile and ChromaTOF Sync can identify differences between samples to compare artifacts and identify biomarkers.
Let LECO help you
find the right instruments for your needs.
If you want to learn more about our products and solutions for food analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Explore the Fascinating World of Separation Science
The very first GC-MS was a GC-TOFMS which was built in 1947. The information it provided was much too large to record, and it was not until the mid-1990s when LECO introduced the first fast GC-TOFMS, that GC-TOFMS became a useable tool for researchers and analysts. Followed a few years later by LECO’s introduction of the first GC×GC-TOFMS.
Today, LECO’s Separation Science products are recognised across the globe as leading advanced technology innovations in TOFMS Mass Spectrometry and Comprehensive two-dimensional Chromatography.
PEGASUS® BT GC-TOFMS
GC Time-Of-Flight Mass Spectrometer
Today‘s laboratories are being asked for more everyday – more samples run, more data acquired, more chemical information processed, and more results achieved – all in less time, for less money. ...
The Pegasus BT allows you to achieve all you need from a single sample run, while powerful and user-friendly ChromaTOF® software processes your data and removes the guesswork involved with analyte identification, quantitation, and reporting. The Pegasus BT gives users more uptime, better data, and an increase in overall productivity and efficiency.
A time-of-flight mass spectrometer (TOFMS) is ideal for discovering new compounds in your sample, quantifying targeted compounds in complex samples, and increasing throughput with fast chromatography.
► Download the free whitepaper and brochure
PEGASUS® BT 4D GC×GC-TOFMS
GC×GC Time-Of-Flight Mass Spectrometer
The Pegasus BT 4D offers enhanced sensitivity by coupling our benchtop Pegasus BT with a high-performance GC×GC modulation system. This combination gives the Pegasus BT 4D the ability to interrogate challenging samples ...
... where the best sensitivity is needed. Unique and powerful software and hardware features simplify quantitation, while also dramatically making GC×GC easy-to-use and understand. Our thermal modulation system, the QuadJet™, is recognised as the gold standard in GC×GC modulation, providing the highest sensitivity available on the market - ideal for analysing the most complex samples.
One of the main advantages of LECO’s GC×GC-TOFMS is its ability to provide vastly improved peak capacity and resolution than traditional GC-MS systems. It also offers comprehensive information about the sample by separating compounds based on two different properties (volatility and polarity). Combining GC×GC with TOFMS is an ultimate solution for the analysis of complex samples.
► Download the free brochure
PEGASUS® GC-HRT+
High Resolution Time-Of-Flight Mass Spectrometer
Now with even more sensitivity than ever before, the Pegasus GC-HRT+ is the perfect tool for meeting the challenges of today’s highly complex analytical demands. ...
This high-resolution mass spectrometer features industry leading mass accuracy, full mass range acquisition with exceptional speed, full mass range acquisition with exceptional speed, isotopic abundance and mass resolution, all available in a single injection.
Folded Flight Path® (FFP®) technology and a novel data acquisition system enables simultaneous resolutions of over 50,000 FWHM, mass accuracies less than 1 ppm, and acquisition rates up to 200 spectra/second, without the need to adjust tuning or parameters. Thus, facilitating rich analyte finding and high-confidence analyte identification.
► Download the free brochure
PEGASUS® GC-HRT+ 4D
HR GC×GC Time-Of-Flight Mass Spectrometer
The Pegasus GC-HRT+ 4D combines the highest performance GC×GC and TOFMS tools on the market with High Resolution Deconvolution® (HRD®). Ideal for the most complex samples, ...
... users are able to find more analytes than ever before and confidently identify unknown components.
The Pegasus GC-HRT+ 4D takes advantage of four dimensions of separation and resolution:
- 1st dimension chromatographic resolution
- 2nd dimension chromatographic resolution
- High mass resolution and exceptional mass accuracy
- High Resolution Deconvolution (HRD) from the leaders in deconvolution
ChromaTOF brand software, designed specifically for HRT+ instrumentation and GC×GC support, adds advanced qualitative and quantitative capabilities to an all-in-one user-friendly data system.
► Download the free brochure
Examples of LECO Separation Science Applications
Petroleum
Comprehensive Two-Dimensional Gas Chromatography (GC×GC) has proven to be an extremely valuable analytical technique for the petroleum industry due to its ability to substantially increase the chromatographic peak capacity beyond that of traditional single-dimension gas chromatography. Pairing GC×GC with Time-of Flight Mass Spectrometry (TOFMS) provides unsurpassed characterization capabilities due to the separation power of GC×GC and the ability of TOFMS to provide rich data.
Food Testing
The characterization and safety testing of food and food constitutions can be extremely challenging depending on the complexity and the matrix. The LECO GC×GC TOFMS technology provides a highly powerful separation and remarkable identification allowing for improved workflows. More insights thanks to the advanced technology in combination with LECO’s ChromaTOF® brand software deconvolution algorithm and advanced data analysis tool will improve your Food Quality & Safety Testing and Food R&D. Here we demonstrate the aroma analsyis of two types of coffee and coffee packaging and filter leachates.
Perfume and Cosmetics
LECO‘s GC×GC-TOFMS is a valuable asset in the production of cosmetics and perfumes that align with Islamic principles. It can be used to identify the ingredients and detect any prohibited substances such as alcohol or non-halal animal-derived ingredients.
Environmental Analysis
Microplastics are an emerging pollutant which are widely distributed in the environment. Understanding the impact of their growing prevalence on the environment and human health is an important field of research. LECO‘s GC×GC-TOFMS can be used to monitor environmental pollution and air and water quality thus aiding to enforce regulations and ensure the preservation of our environment.
Metabolomics
LECO’s key advantage is the ability to identify and discover more metabolites than other similar technologies. Our speed of full-scan acquisition is unrivaled, and when combined with the power of LECO’s ChromaTOF® brand software deconvolution algorithm, allows an unprecedented characterisation of the biological systems under study. Our instrumentation has been validated by the industry‘s most demanding researchers.
Extractables and Leachables
The characterization of extractable and leachable components from a wide range of materials is an important area of research. Information about extractable and leachable components from packaging and delivery devices for pharmaceutical products is a particular area of growing interest. Analytical testing results on this topic are part of many regulatory submission requirements to the FDA. ...
USP 1663 provides guidance on extractables testing and a variety of analytical approaches can meet compliance. High resolution MS is often considered necessary for identification of unknowns, and sample complexity and low-level detection continue to challenge these analyses. Here, we demonstrate a workflow that uses comprehensive two-dimensional gas chromatography (GC×GC) with HR-TOFMS to help address these challenges.
► App Note | Characterizing Extractables by GC×GC & HR-TOFMS
FAQ – Separation Science
Answer:
Gas chromatography separates components in a mixture by utilizing a thin silica tube coated with a stationary phase. The components, carried by a gas (the mobile phase), move at different speeds based on their affinities for the stationary phase. This differential migration leads to the separation of the components, allowing for their individual analysis and identification.
Alternative response:
- Gas chromatography is a technique for separating a mixture of volatile analytes
- The analytes are transported by a mobile phase (the carrier gas)
- Become distributed between the mobile phase and a stationary phase
- The Stationary Phase is attached to the inside of a very fine column
- Phases are typically characterised by their polarity
- A polar analyte will be retained by polar column for longer than a non-polar analyte
- and vica versa
Answer:
LECO uses Agilent 8890 chromatography. The gas chromatograph includes the following features:
- Compatibility and perfect integration with the mass spectrometer
- Automatic regulation of gas flows
- Agilent supported inlets: Split/Splitless (SSL), Multimode (MMI), Programmable temperature Vaporizer (PTV) etc.
- Programmable oven, up to 450 °C
- Chromatograph compatible with Fast-GC
- The GC is completely controlled by and integrated into LECO’s ChromaTOF software
Answer:
The LECO mass spectrometer is connected to the GC via a heated transfer line. The LECO GC-TOF allows you to have a 'full range' acquisition, without compromise, then a targeted and/or non-targeted data exploitation depending on what you want to do.
It consists of an EI (Electronic Impact) source, a 70 cm flight tube, a reflectron and a detector. Vacuum is provided by an internal turbomolecular pump connected to an external secondary pump.
Answer:
The mass range of the Pegasus BT is from 10 to 1500 m/z. All masses are collected all the time, unlike quadrupole instruments that collect a single mass at a time (quadrupole scanning mode is single ion monitoring, SIM, quickly scanning across the mass range).
Answer:
GC×GC-TOFMS can detect discrepancies in the composition of food products, helping to expose fraudulent claims of Halal certification and ensure consumer confidence in authentic Halal products.
Answer:
By examining the chemical composition of inks and pigments, GC×GC-TOFMS provides insights into the materials used in Islamic calligraphy and manuscripts, aiding in their preservation and authentication. An example of similar work can be read in this publication on analysing the paints used by Leonardo Da Vinci.
Answer:
LECO’s GC×GC-TOFMS system utilizes two columns with different separation mechanisms, providing enhanced chromatographic resolution for the analysis of complex mixtures. In one dimension the analytes are separated by polarity, or according to boiling point. An additional dimension separates according to an alternative property, of which there are many. This results in a 3D image – the two dimensions of separation and the abundance of the analytes in the third dimension.
Answer:
LECO's StayClean® ion source originates in the requirement for a fast source to match the speed of the TOFMS. Accomplished by reducing ion to ion interactions, such as with the walls of the source. The source was thus designed without walls – so there is nothing to clean. Massively reduced downtimes, especially for complex matrices and more reproducible results.
Answer:
Yes! With superior separation power and precision, LECO’s GC×GC-TOFMS system can uncover hidden details and confidently identify components, even in the most intricate mixtures:
- Increases detectability
- Removes analytes from matrix interference
- Separates co-elluting peaks
- Creates cleaner peaks, which match closer with libraries
- Creates structured chromatograms thus further improving identification confidence
Answer:
The cryogenic Quad Jet modulator consistently delivers reproducible quantitative results not only within the lab but also between labs worldwide. This is achieved because:
- There are two cold jets. So, eluent from the primary column does not flow into the secondary column by mistake
- The distance between cold zones is identical in every system worldwide, unlike other systems that require manual adjustment and intervention
- The modulation is completely computer controlled. This along with the 2 separate cold zones, allows for variable modulation periods in the same analysis, vastly improving separation across the chromatogram
- In the same way the primary column is temperature controlled in the primary oven, the secondary column is also independently controlled, allowing for total control of the chromatogram along the entire column setup
These four features not only improve separation and control, they are also unique to the LECO QuadJet.
Answer:
By combining comprehensive two-dimensional gas chromatography (GC×GC) with high-speed, high-sensitivity time-of-flight mass spectrometry (TOFMS), LECO's GC×GC-TOFMS can separate and identify the complex mixtures of flavours and fragrances in food samples with detail and precision.
Answer:
Yes! LECO’s GC×GC-TOFMS is an excellent tool for non-intentionally added substances (NIAS) analysis in food safety. It allows for the comprehensive analysis of complex food samples, ensuring the detection and identification of potential contaminants and unwanted substances. For example, LECO’s MOSH/MOAH solution is widely recognised as the most comprehensive and rigorous analyser for mineral oil contamination in food stuffs.
Answer:
LECO’s GC×GC technology utilizes two stages of separation, significantly increasing resolution and analysis power compared to traditional gas chromatography. This allows for the detailed separation and identification of complex mixtures with unparalleled precision.
Answer:
LECO’s TOFMS technology offers excellent sensitivity, speed, and resolution in mass spectrometry. By fragmenting and ionizing analyte molecules and separating the fragments based on their mass-to-charge ratio, LECO's TOFMS enables highly accurate identification and detection of compounds in samples. The system not only records to a computer at high speed, it detects at a rate of 32,000 Hz thus producing a very high level of accuracy.
Answer:
GC×GC-TOFMS enables the analysis of dietary supplements for the presence of non-compliant ingredients, such as animal-derived gelatine, ensuring that the products meet the strict requirements of Halal certification.
Answer:
GC×GC-TOFMS is a valuable tool for monitoring air and soil quality near Islamic sacred sites, identifying pollutants that may pose a risk to their preservation and guiding conservation efforts. As an example, Imperial College London have utilised a LECO Pegasus BT 4D to identify microplastics in the air of London. You can read about it here.
Answer:
LECO’s GC×GC-TOFMS system utilizes Time-of-Flight Mass Spectrometry (TOFMS), which provides high-speed detection of ionized compounds based on their mass-to-charge ratio.
Answer:
LECO provides software for data analysis, enabling compound identification, quantification, and other types of analysis based on the mass spectra obtained from the TOFMS.
Answer:
LECO’s StayClean ion source, a standard feature in every Pegasus BT GC-TOFMS and GC×GC-TOFMS system, flushes neutrals and contaminants continuously. This virtually eliminates the need for routine maintenance, allowing you to spend less time on upkeep and more time on your research.
Answer:
Sample handling is crucial in GC-MS analysis. LECO employs advanced sample handling robots called Autosamplers that can handle samples in three dimensions of space. These robots ensure precise and consistent sample preparation, ranging from simple liquid injections to complex processes like chemical reactions, extractions, and accurate dilutions.
Answer:
The first GC-MS was a GC-TOFMS developed in the 1950s. However, the technique was too powerful for data recording at the time. In the mid-1990s the first GC-TOFMS capable of recording the data for processing was developed by LECO. This breakthrough in fast GC-TOFMS technology allowed researchers and analysts to utilize the capabilities of GC-TOFMS for their analytical needs.
Answer:
By combining two-dimensional separation, robust ionization, and high-speed TOFMS detection, and patented deconvolution algorithms LECO's GC×GC-TOFMS system offers a powerful solution for analysing complex mixtures with enhanced resolution, sensitivity, and separation power.
Answer:
By analysing the chemical composition of materials used in ancient Islamic artifacts, GC×GC-TOFMS assists in determining their authenticity, providing valuable insights into historical and cultural heritage. The chemical composition of such artifacts are extremely complex so utilising multidimensional chromatography techniques with high speed TOFMS, a chemical profile can be created. Furthermore, LECO’s post processing software packages, ChromaTOF Tile and ChromaTOF Sync can identify differences between samples to compare artifacts and identify biomarkers.
Let LECO help you
find the right instruments for your needs.
If you want to learn more about our products and solutions for food analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Expedite Gas Chromatography Analysis with Hydrogen
For years, helium has been the go-to choice as a carrier gas for mass spectrometers due to its well-known benefits. However, its limited supply and varying costs have posed significant challenges for labs worldwide.
LECO has conducted extensive research on the use of hydrogen as a carrier gas for GC-TOFMS analysis. We have developed innovative method transfer approaches to ensure a smooth and efficient transition to hydrogen. With our proven expertise in the hydrogen conversion process, we can help labs of all sizes achieve increased chromatographic throughput without sacrificing the sensitivity and accuracy they demand.
As the supply of helium continues to dwindle, the use of hydrogen as a carrier gas for GC applications has become an increasingly attractive option. With both benefits and drawbacks to consider, it requires the expertise of a dedicated team to determine the optimal approach.
In the following sections, we will share the details of our approach, including the method transfer approaches used, the technological benefits, and application examples. At LECO, we understand the importance of providing comprehensive information and support. That's why we have put together a range of resources specifically on hydrogen conversion, to help you make an informed decision.
Don‘t miss out on this unique opportunity!
We know how valuable your time is, so we‘re bringing the experts and resources closer to you to show you how LECO instrumentation and hydrogen carrier gas can revolutionize your analysis, with live demos of our instruments and software.
Instrument Portfolio for Hydrogen carrier gas
We understand that the conversion from helium to hydrogen carrier gas can be a crucial step in mass spectrometry, where speed and sensitivity are of utmost importance. At LECO, we take pride in designing our PEGASUS® mass spectrometers to deliver exceptional performance in Fast GC applications with both helium and hydrogen carrier gas. Our instruments are built to provide high-speed analysis without compromising sensitivity, making them the ideal choice for labs looking to switch to hydrogen. In addition, with our innovative StayClean® Ion Source technology, you can be confident that your instrument will operate at peak efficiency, free from the need for frequent cleaning and maintenance.
On-demand Videos & Presentations
Helium is becoming an increasingly limited natural resource; using Hydrogen to achieve increased chromatographic throughput in GC applications is attractive. Both have advantages and disadvantages. LECO has for years investigated the use of Hydrogen as a carrier gas for GC-TOFMS analysis. In the following we are going to present you the method transfer approaches used, the technological benefits, and application examples.
► „Fast GC / Hydrogen Method Transfer Overview & Application Examples“
by Nick Jones, Sebastiano Panto, Lena Dubois, Joe Binkley (LECO Corporation, St. Joseph, MI USA)
Please click here for watching the video ...
► „GC×GC Analysis with Chroma TOF Tile“
by Lena Dubois (LECO ETAC, Berlin, GER)
Please click here for watching the video ...
► „GC-MS Analysis Workflow utilizing ChromaTOF Sync“
by Liz Humstom-Fulmer (LECO Corporation, St. Joseph, MI USA)
Please click here for watching the video ...
► „Discovery Workflow Best Practices for Environmental Contaminants“
by Albert T. Lebedev (Lomonosov Moscow State University), David E. Alonso (LECO Corporation, St. Joseph, MI USA)
Please click here for watching the video ...
Webinar: Enhance Your GC-MS Workflow
With ever-increasing demands on your time, labor, and resources, optimizing your workflow is essential. Learn best approaches from GC-TOFMS experts to enhance your one- and two-dimensional gas chromatography applications (GC-MS and GC×GC-MS) in this webinar.
Webinar: Designed for Speed – A Fast GC Forum
Could your lab use to speed up your GC analysis? In the „Designed for Speed“ forum, a panel of experts explore advancements in gas chromatography and mass spectrometry technology and how laboratories can speed up their analysis.
Library – Hydrogen Carrier Gas Publications
Read our following publications and discover more about GC-TOFMS analyses with hydrogen as a carrier gas.
Thank you for submitting the form. You now have access to all files.
App Notes:
Hydrogen-based GC-TOFMS Analysis
The shortage of helium and its increased costs are encouraging laboratories to find suitable alternatives. Learn how LECO achieves quality results utilizing Hydrogen as a carrier gas.
Poster:
„Utilizing unique TOF-MS technology and hydrogen carrier gas for fast GC-MS“
How many sample runs can you fit into your day? With a few simple changes, LECO‘s Pegasus BT can drastically speed up gas chromatography throughput. A faster time-of-flight analysis doesn‘t need to mean lower quality results.
Article:
„A green and sustainable method for Capsicum [...] using H2 Carrier Gas“
Learn how scientists from the University of Messina (Italy) increased their sustainability and „greenified“ their pepper analyses utilizing LECO separation science instruments.
Interested?
We welcome the opportunity to discuss how hydrogen conversion can benefit your lab.
Get in touch with us today to learn more.
If you want to learn more about our products and solutions for Fast GC analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Expedite Gas Chromatography Analysis with Hydrogen
For years, helium has been the go-to choice as a carrier gas for mass spectrometers due to its well-known benefits. However, its limited supply and varying costs have posed significant challenges for labs worldwide.
LECO has conducted extensive research on the use of hydrogen as a carrier gas for GC-TOFMS analysis. We have developed innovative method transfer approaches to ensure a smooth and efficient transition to hydrogen. With our proven expertise in the hydrogen conversion process, we can help labs of all sizes achieve increased chromatographic throughput without sacrificing the sensitivity and accuracy they demand.
As the supply of helium continues to dwindle, the use of hydrogen as a carrier gas for GC applications has become an increasingly attractive option. With both benefits and drawbacks to consider, it requires the expertise of a dedicated team to determine the optimal approach.
In the following sections, we will share the details of our approach, including the method transfer approaches used, the technological benefits, and application examples. At LECO, we understand the importance of providing comprehensive information and support. That's why we have put together a range of resources specifically on hydrogen conversion, to help you make an informed decision.
Don‘t miss out on this unique opportunity!
We know how valuable your time is, so we‘re bringing the experts and resources closer to you to show you how LECO instrumentation and hydrogen carrier gas can revolutionize your analysis, with live demos of our instruments and software.
Instrument Portfolio for Hydrogen carrier gas
We understand that the conversion from helium to hydrogen carrier gas can be a crucial step in mass spectrometry, where speed and sensitivity are of utmost importance. At LECO, we take pride in designing our PEGASUS® mass spectrometers to deliver exceptional performance in Fast GC applications with both helium and hydrogen carrier gas. Our instruments are built to provide high-speed analysis without compromising sensitivity, making them the ideal choice for labs looking to switch to hydrogen. In addition, with our innovative StayClean® Ion Source technology, you can be confident that your instrument will operate at peak efficiency, free from the need for frequent cleaning and maintenance.
On-demand Videos & Presentations
Helium is becoming an increasingly limited natural resource; using Hydrogen to achieve increased chromatographic throughput in GC applications is attractive. Both have advantages and disadvantages. LECO has for years investigated the use of Hydrogen as a carrier gas for GC-TOFMS analysis. In the following we are going to present you the method transfer approaches used, the technological benefits, and application examples.
► „Fast GC / Hydrogen Method Transfer Overview & Application Examples“
by Nick Jones, Sebastiano Panto, Lena Dubois, Joe Binkley (LECO Corporation, St. Joseph, MI USA)
Please complete our form to watch the videos on-demand.
► „GC×GC Analysis with Chroma TOF Tile“
by Lena Dubois (LECO ETAC, Berlin, GER)
Please complete our form to watch the videos on-demand.
► „GC-MS Analysis Workflow utilizing ChromaTOF Sync“
by Liz Humstom-Fulmer (LECO Corporation, St. Joseph, MI USA)
Please complete our form to watch the videos on-demand.
► „Discovery Workflow Best Practices for Environmental Contaminants“
by Albert T. Lebedev (Lomonosov Moscow State University), David E. Alonso (LECO Corporation, St. Joseph, MI USA)
Please complete our form to watch the videos on-demand.
Webinar: Enhance Your GC-MS Workflow
With ever-increasing demands on your time, labor, and resources, optimizing your workflow is essential. Learn best approaches from GC-TOFMS experts to enhance your one- and two-dimensional gas chromatography applications (GC-MS and GC×GC-MS) in this webinar.
Webinar: Designed for Speed – A Fast GC Forum
Could your lab use to speed up your GC analysis? In the „Designed for Speed“ forum, a panel of experts explore advancements in gas chromatography and mass spectrometry technology and how laboratories can speed up their analysis.
Library – Hydrogen Carrier Gas Publications
Read our following publications and discover more about GC-TOFMS analyses with hydrogen as a carrier gas. We kindly ask you to submit our form. Afterwards you‘ll get access to all files.
App Notes:
Hydrogen-based GC-TOFMS Analysis
The shortage of helium and its increased costs are encouraging laboratories to find suitable alternatives. Learn how LECO achieves quality results utilizing Hydrogen as a carrier gas.
„Analsysis of Teatree Oil“
„Citrus Essential Oils“
Poster:
„Utilizing unique TOF-MS technology and hydrogen carrier gas for fast GC-MS“
How many sample runs can you fit into your day? With a few simple changes, LECO‘s Pegasus BT can drastically speed up gas chromatography throughput. A faster time-of-flight analysis doesn‘t need to mean lower quality results.
Article:
„A green and sustainable method for Capsicum [...] using H2 Carrier Gas“
Learn how scientists from the University of Messina (Italy) increased their sustainability and „greenified“ their pepper analyses utilizing LECO separation science instruments.
Interested?
We welcome the opportunity to discuss how hydrogen conversion can benefit your lab.
Get in touch with us today to learn more.
If you want to learn more about our products and solutions for Fast GC analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Attention All Aroma Enthusiasts!
The LECO Aroma Roadshow 2023 has concluded, and it was a remarkable journey that brought the world of aroma analysis closer to professionals across Europe. At LECO, we understand the value of your time, and our goal was to make expertise more accessible. We're thrilled to have had the opportunity to meet with you in person and demonstrate how LECO instrumentation and the use of hydrogen carrier gas can elevate your analytical capabilities.
Our team of friendly and knowledgeable application specialists provided live demonstrations of our cutting-edge instruments and software, enriching your understanding of aroma analysis. We are grateful for your active participation and insightful questions, which made this event a success.
While the LECO Aroma Roadshow 2023 has concluded, our commitment to advancing your knowledge and expertise continues. Stay tuned for more updates, resources, and future events from LECO
For any questions or further information, please contact: This email address is being protected from spambots. You need JavaScript enabled to view it.
More about aroma analysis
If you missed our roadshow and want to delve deeper into the world of aroma analysis, please visit our aroma resources page. There, you'll find valuable insights and information to enhance your understanding of this fascinating field.
Program
At the LECO Aroma Roadshow, each event stop was thoughtfully designed to maximize the experience and deliver valuable insights for all attendees. The goal was to make the most of everyone's precious time.
During the dedicated time slots, our experts provided one-on-one assistance, addressing specific needs and answering questions that arose. Attendees had the chance to witness our instruments in action, all without disrupting their busy schedules.
The event was a collaborative exploration of data, where participants saved time and gained valuable insights. It was a unique opportunity for personalized guidance from experts tailored to sample data.
Please click on the image to enlarge.
How can we do this?
LECO instrumentation is robust and reliable, allowing us to set up methods in advance that will run in any environment.
Using hydrogen carrier gas vastly speeds up the acquisition process reducing run times by up to 75%.
The instrument will be set up to run your sample allowing our conversation to revolve around your data.
Sample
Our Sales Engineer will be in contact with you and will provide instructions on how to prepare your samples for live measurements. They will provide all the necessary information and collaborate with our team of application specialists to help you achieve exceptional results. With the goal of empowering your results, we're committed to ensuring your measurements are accurate and reliable. Should you not have specific requests, our team will also prepare test samples for measurement.
Roadshow Venues
Completed
18th or 19th April
Stockport, UK
LECO Instruments Ltd.
Unit 7, Rhino Court, Station View
Bramhall Moor Lane, Hazel Grove
Stockport SK7 5ER
Completed
26th or 27th April
Cambridge, UK
Element Cambridge
(formerly Anatune)
Unit 4, Wellbrook Court
Girton Rd, Girton
Cambridge CB3 0NA
Completed
2th or 3th May
Oberhausen, GER
SIM Scientific Instruments
Manufacturer GmbH
Im Erlengrund 21-23
46149 Oberhausen
Completed
25th or 26th May
Ferrara, IT
University of Ferrara
Via Luigi Borsari, 46
44121 Ferrara FE
Completed
25th or 26th May
Berlin, GER
LECO EATC
Max-Dohrn Strasse 8-10
Biotechpark, Building B 5.2
10589 Berlin
Completed
7th or 8th June
Liège, BEL
University of Liège
Place du 20 Août 7
4000 Liège
Completed
29th or 30th June
Lyon, FR
Université de Lyon
92 Rue Pasteur
69007 Lyon
Completed
12th September
Messina, IT
Università degli Studi di Messina
Via G. Palatucci SNC
98168 Messina
Completed
14th or 15th November
Berlin, GER
LECO EATC
Max-Dohrn Strasse 8-10
Biotechpark, Building B 5.2
10589 Berlin
Let LECO help you find the right instruments for your need.
If you want to learn more about our products and solutions for aroma analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Enhance your Food Analysis
LECO instruments analyse the quality, safety, and nutritional value of many foods and feeds – from raw foods to final consumer-ready products. Benefit fom the advantages of our state-of-the-art solutions for your individual food analysis. Elevate your results and save your time.
Specific Advantages Including
- Moisture Determination – Loss on drying automated up to 16 samples simultaneously
- MOSH/MOAH Determination – Identify and quantify the source of contamination
- Detection of Pesticides – Even in the most difficult matrices
- Protein Determination after Dumas – Replacement of Kjeldahl; Results in ≈ 3 minutes fully matrix independent
- Aroma Profiling – Identify what you smell, but never see
Unlock the 2023 special issue of FoodLab Magazine now – Exclusively Available Here!
Explore our exclusive collection of expert articles on aroma, moisture & ash, MOSH/MOAH, and protein, developed in collaboration with FoodLab Magazine. Download now for the latest insights in the food industry.
Instrument Portfolio for Food Analysis
Your Solution For Cost Effective Food Analysis
Check out our broad product portfolio for food safety, nutrition, and moisture analysis. Benefit from the advantages of our state-of-the-art solutions for your individual food analysis.
MOSH MOAH Determination
Whatever your sample preparation workflow requirements are, harness the power of LECO GC×GC & TOF technology to solve the complex challenges of MOSH/MOAH Analysis.
Protein Determination
Protein determination with LECO after the principle of Dumas can be very easy and convenient. LECO has the perfect solution with the 828 and the 928 productline.
Determination of Moisture/Ash/Loss on Drying
An accurate determination of moisture content in food or agricultural products provides important information related to the food quality and safety.
Aroma Analysis
Quantify and screen samples with a single injection using LECO two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC TOFMS).
White Paper | Protein Analysis - Dumas Vs. Kjeldahl
Have you ever wondered about this old discussion about „Dumas and Kjedahl“ and which one fits better to your needs in the field of protein analysis?
Read our lates white paper related to protein analysis by comparing the methods "Dumas vs. Kjeldahl". Get a concise overview about the theories of operation, and learn how the benefits of a LECO Dumas determinator can impact your workflow.
Let LECO help you find the right instruments for your needs.
If you want to learn more about our products and solutions for food analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
LA2PC | LECO Analytical Applications Poster Competition
With the aim of improving our understanding and knowledge of LECO users’ work and research, LECO Europe hosted the LECO Analytical Poster Competition 2020. It was very successful, as we received a variety of interesting posters from our LECO users and customers featuring various applications and fields of interest. Please see below all entries in the different fields. For a higher resolution please complete our login-form. To download the complete poster booklet with all submissions, please click on the button below.
Elemental Analysis Entries
"Macro, micro? Comparison of DUMAS analysers in real conditions"
Jean-Michel Romnee | CRAW, Walloon Agricultural Research Centre
Charles Ojeimi | ELEMENTAR France
Alexis Sorokovsky | LECO France
Please click here to view high-resolution.
"Trumac CN, a tool to evaluate the quality of fertilizers humic coating"
Jean-Michel Romnee | CRAW, Walloon Agricultural Research Centre
Please click here to view high-resolution.
"IGA Fractional O/N/H Analyses of Powder Feedstocks for Additive Manufacturing"
Boris Albouy, Jérémy Berot-Lartigue, Nicole Cuq, Xinwei Wang | Eurofins EAG Laboratories
Please click here to view high-resolution.
"Analysis of Tic-based Alloys Prepared by Mechanical Alloying and Spark Plasma Sintering"
Mohsen Mhadhbi | National Institute of Research and Physical-Chemical Analysis
Frédéric Schoenstein, Noureddine Jouini | Paris 13 University
Please click here to view high-resolution.
"Development of a method to analyze Aluminum alloys powders using the gas analyzer LECO ONH836"
Jimmy Dardinier, Thibaut Turlan, Agathe Deborde | MetaFensch, IRT-M2P
Please click here to view high-resolution.
"LECO Boat Crucible as an Aid to Analysis of Total Organic Carbon (TOC) Content in Rock Samples"
Doaa A. Mousa, Shereen A. Naseef, Amr M. Shehata | Egyptian Petroleum Research Institute (EPRI)
Please click here to view high-resolution.
"LECO Spectrum System 2000"
Walid A. Makled | Egyptian Petroleum Research Institute (EPRI)
Please click here to view high-resolution.
"Pretreating lignocellulosic biomass wastes for the next generation of solid fuels"
Karl Hornsby, Martin J. Taylor, Vasiliki Skoulou | University of Hull
Peter Hurst | Biorenewables Development Centre (BDC)
Simon Walker | Jesmond Engineering Ltd, Brough Business Centre
Please click here to view high-resolution.
"Moisture, Volatiles and Ash in Biofuels with the TGA801"
[No Competitor] Michael Jakob | LECO EUROPE
Please click here to view high-resolution.
Separation Science Entries
"VOCs from Wood Fibers Insulation Materials"
Dorota Fuczek, Jaroslaw Szuta, Krystian Szutkowski | STEICO Sp. z o.o.
Please click here to view high-resolution.
"Analytical Pyrolysis Coupled with Chemometric Methods"
Marcin Sajdak, Roksana Muzyka, Maciej Chrubasik | Institute for Chemical Processing of Coal
Please click here to view high-resolution.
"Investigation of Baijiu Aroma Types and Regional Origin"
Xi He, Henryk. H. Jelen | Poznan University of Life Sciences
Please click here to view high-resolution.
"Pyro-GC×GC-TOFMS/FID for the study of organic matter in unconventional hydrocarbon reservoirs"
E. Leushina, E. Kozlova, T. Bulatov, M. Spasennykh | Skoltech
Please click here to view high-resolution.
"Detection of Honey Bee Disease Through Monitoring Shifts in Volatile Profiles"
Margaret Gill, Falko Drijfhout | Keele University
Please click here to view high-resolution.
"Green and Sustainable Catalysis Using a Pd Doped Biochar under Mild Conditions"
Jamie P. Southouse, Karl Hornsby, Kin Wai Cheah, M. Grazia Francesconi, Vasiliki Skoulou, Martin J. Taylor | University of Hull
Please click here to view high-resolution.
If you want to learn more about our products and solutions for your lab, book a free ticket to our LECO Virtual Trade Show, or schedule an Online Demo for a deeper insight in our instruments.
Metabolomics presents challenges for both the analytical methods used and the data reduction required to interpret the results. No single analytical technique can be used for complete characterisation of the metabolome, and no metabolome has been completely characterised. However, GC-MS provides an established method to analyse the primary metabolome, whereas LC investigates the secondary and tertiary metabolites.
LECO Solutions For Aroma Analysis
Finding the sources of off-flavors is easier than ever with LECO GC-MS technology. Quantify and screen samples with a single injection using LECO two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC TOFMS).
Characterize natural fragrances; matrix and unravel complex essential oils. Identify taints and off-flavors to allow the improvement of quality and profitability. See specific examples with our app notes and webinars to learn how LECO's GC and GC×GC technology can empower your laboratory, or get detailed information about LECO's instruments for sensory, flavor, and fragrance analysis.
In the following, you are going to find a content compendium according to aroma analysis. For some content, we kindly ask you to submit our form. After filling it out once, you'll get access to all the files.
Product portfolio
PEGASUS® BT GC-TOFMS and PEGASUS® BT 4D GC×GC-TOFMS
The tried-and-tested reliability and durability of our Pegasus brand in a convenient benchtop unit gives you more uptime, improved chemical data, and an increase in overall productivity and efficiency.
Recent Events / On Demand Presentations
► "Enhanced GC-MS Workflow Solutions Webinar"
Learn how state of the art instrument and software solutions come together, to enhance your one- and two-dimensional gas chromatography applications (GC-MS and GC×GC-MS).
Watch the video ...
► "1st LECO European Wine Workshop"
Watch the various presentation of experts on GC-TOF-MS / GC×GC-TOF-MS for wine analyses and learn how GC-MS can enhance your daily analysis.
Watch the video ...
► "Challenges and Solutions in Aroma Profiling (MDCW 2022)"
Did you miss LECO's webinar during MDCW 2022?
Lena M. Dubois' presentation discussing solutions to challenges faced in ...
Watch the video ...
► "Towards even better tasting veggie foods"
Hans-Gerd Janssen (Unilever) and Ed Rosing (Wageningen University) discuss untargeted GC×GC-MS data interpretation for advancement ...
Watch the video ....
► "Understanding Food Off-Flavors and Malodors"
Utilizing Gas Chromatography-Olfactometry (GC-O) can help identify active odor compounds in complex mixtures. But, what happens if GC-O ...
Watch the video ...
► "Flavor Ingredient Analyses through GCMS"
Marlene Moskowitz, PhD, Analytical Chemist at McCormick, discusses how their labs leverage Gas Chromatography Mass ...
Watch the video ...
Aroma Analysis Library & Publications
Learn more about our solutions for aroma analysis and read our Application Notes. In the following, you are going to find a content compendium.
Application Notes
PEGASUS® BT GC-TOFMS
- Pairing Olfactory Detection with GC-MS to Clarify Identification of Isomers
- Characterization and Comparison of Whiskey Aroma Profiles with GC-TOFMS and Sync
- Differentiation of Baijiu Spirits
- Analysis of Citrus Essential Oils
- Comparison of Traditional Chardonnay and Buttery Chardonnay
- Sensitive Analysis of Tea Tree Essential Oil
- Brewery Process Monitoring
- Essential Oil Characterization
- Chemical Aroma Profile of Dark Chocolate Bar
- Track Aging of an American IPA Beer at Different Storage Temperatures
- Monitoring of Furan Derivates and Key Aroma Species Simultaneously in Coffee and Coffee Substitutes
Application Notes
PEGASUS® BT 4D GC×GC-TOFMS
- Statistical Differentiation of Baijiu Spirits Using SPME-GC×GC-TOFMS and ChromaTOF® Tile Software
- Workflow for the Assessment of Key Aroma Compounds of Pumpernickel Bread Variations
- Comprehensive Evaluation of Scotch Whisky Aroma Profiles Using SPME-GC×GC-TOFMS
- Pesto Aroma Profile SPME
- Pesto ChromaTOF Tile SPME
- Frankincense and Myrrh: Visual Characterization and Comparison of Essential Oils
- Characterization of Citronella Essential Oil
- Characterization and Roast Level Differentiation of Coffee
- Differentiation of Honey Aroma Profiles
- Improved Characterization and Differentiation of Perfume Samples
- Differentiating Original-Brand and Imitation Perfumes with GCxGC-TOFMS and ChromaTOF Tile
eFoodLab Article | New Dimensions in Beverage Characterisation
In this issue, eFoodLab published an interview with Dr. Geraint (Taff) Morgan of the Applied Science & Technology Group at The Open University, UK, who discussed his team's activities as part of their impact agenda to develop and deploy novel analytical solutions for beverage products within the industry.
eFoodLab Article | Trends and Patterns in the Alcoholic Beverage Industry
eFoodLab spoke to some key players to investigate current trends and patterns of work in the sector and valuable insights were provided by "In The Welsh Wind", a distilled spirits company forging new and alternative approaches to produce authentic and sustainable Welsh Whiskey, "He Stringer Flavours", a flavour and fragrance company innovating flavour formulations to provide brands and consumers with increased choice and quality.
eFoodLab Article | Innovative Beer crafted from unsold bread
eFoodLab is talking about 'Cacciatori di Briciole' beer, exploring its aromatic intricacies through advanced gas chromatography techniques, a testament to sustainable brewing innovation.
Further Instrument Portfolio
Browse our line up of scientific analytical products sensory, flavor, and fragrance analysis to find the appropriate instrument for your specific purposes.
LECO's QuadJet™ SD is the ideal solution for samples which arrive in your lab. By combining the sensitivity of Flame Ionization Detection (FID) with the increased chromatographic resolution of comprehensive two-dimensional gas chromatography (GCxGC), the QuadJet SD delivers a better measure of the actual components of your sample than a straight GC analysis. No other system available on the market can deliver the same reduction in noise and error as the QuadJet SD.
Available exclusively from LECO, our L-PAL3 autosampler offers increased vial capacity, discrimination-free GC injections (ultrafast injections), an automatic tool exchange to switch between injector types (liquid, headspace, or SPME), minimized carryover, and the sensing of vial bottoms to avoid mis-injections.
The Easier Way To Make GC×GC Part Of Your Every-Day Analysis
Simply GC×GC from LECO is a free tool designed to walk you through the steps of creating an optimized GC×GC method for your complex samples. Create a GC×GC method from scratch, or convert an existing 1D method to GC×GC.
GC×GC Flow Modulator
Our innovative FLUX GC×GC flow modulator was designed with one goal in mind—to make GC×GC more routine, accessible, and easier for you.
Thermal modulation delivers the highest performance of any available modulator for GC×GC. Other types of thermal or valve-based modulators do not match up to the ruggedness, reliability, and performance of LECO's GC×GC modulator.
Ionization Source For Gas Chromatography Mass Spectrometry
The innovative Multi-Mode Source™ (MMS™) takes all of the advantages of the three most common ionization modes – Electron Ionization (EI), Positive Chemical Ionization (PCI), and Negative Chemical Ionization (NCI/ECNI) – and combines them into one easy-to-use source. No more hardware switching, no more alignment issues:
with the MMS, changing ionization modes is as easy as a click of a button.
Developed exclusively by LECO, ChromaTOF® is uniquely designed to meet the needs of today’s laboratory professionals by processing and analyzing the large amounts of data that are acquired with our time-of-flight instruments.
Developed exclusively by LECO, ChromaTOF® is uniquely designed to meet the needs of today’s laboratory professionals by processing and analyzing the large amounts of data that are acquired with our time-of-flight instruments.
Bring the Power of Accurate Mass and Confidence to your Identification Problems
LECO's Identification Grading System (IGS) eases data review by allowing users to quickly see, justify, have confidence in, and report on which chemicals are in a particular sample.
Let LECO help you find the right instruments for your needs.
If you want to learn more about our products and solutions for aroma analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
LECO Solutions For Aroma Analysis
Finding the sources of off-flavors is easier than ever with LECO GC-MS technology. Quantify and screen samples with a single injection using LECO two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC TOFMS).
Characterize natural fragrances; matrix and unravel complex essential oils. Identify taints and off-flavors to allow the improvement of quality and profitability. See specific examples with our app notes and webinars to learn how LECO's GC and GC×GC technology can empower your laboratory, or get detailed information about LECO's instruments for sensory, flavor, and fragrance analysis.
In the following, you are going to find a content compendium according to aroma analysis. For some content, we kindly ask you to submit our form. After filling it out once, you'll get access to all the files.
Product portfolio
PEGASUS® BT GC-TOFMS and PEGASUS® BT 4D GC×GC-TOFMS
The tried-and-tested reliability and durability of our Pegasus brand in a convenient benchtop unit gives you more uptime, improved chemical data, and an increase in overall productivity and efficiency.
Recent Events / On Demand Presentations
► "Enhanced GC-MS Workflow Solutions Webinar"
Learn how state of the art instrument and software solutions come together, to enhance your one- and two-dimensional gas chromatography applications (GC-MS and GC×GC-MS).
Please click here to watch the video.
► "1st LECO European Wine Workshop"
Watch the various presentation of experts on GC-TOF-MS / GC×GC-TOF-MS for wine analyses and learn how GC-MS can enhance your daily analysis.
Please complete our form to watch the video.
► "Challenges and Solutions in Aroma Profiling (MDCW 2022)"
Did you miss LECO's webinar during MDCW 2022?
Lena M. Dubois' presentation discussing solutions to challenges faced in ...
Please complete our form to watch the video.
► "Towards even better tasting veggie foods"
Hans-Gerd Janssen (Unilever) and Ed Rosing (Wageningen University) discuss untargeted GC×GC-MS data interpretation for advancement ...
Please complete our form to watch the video.
► "Understanding Food Off-Flavors and Malodors"
Utilizing Gas Chromatography-Olfactometry (GC-O) can help identify active odor compounds in complex mixtures. But, what happens if GC-O ...
Please complete our form to watch the video.
► "Flavor Ingredient Analyses through GCMS"
Marlene Moskowitz, PhD, Analytical Chemist at McCormick, discusses how their labs leverage Gas Chromatography Mass ...
Please complete our form to watch the video.
Aroma Analysis Library & Publications
Learn more about our solutions for aroma analysis and read our Application Notes. In the following, you are going to find a content compendium. We kindly ask you to submit our form. Afterwards you‘ll get access to all the files.
Application Notes
PEGASUS® BT GC-TOFMS
Please complete the form to get access to all App Notes.
- Pairing Olfactory Detection with GC-MS to Clarify Identification of Isomers
- Characterization and Comparison of Whiskey Aroma Profiles with GC-TOFMS and Sync
- Differentiation of Baijiu Spirits
- Analysis of Citrus Essential Oils
- Comparison of Traditional Chardonnay and Buttery Chardonnay
- Sensitive Analysis of Tea Tree Essential Oil
- Brewery Process Monitoring
- Essential Oil Characterization
- Chemical Aroma Profile of Dark Chocolate Bar
- Track Aging of an American IPA Beer at Different Storage Temperatures
- Monitoring of Furan Derivates and Key Aroma Species Simultaneously in Coffee and Coffee Substitutes
Application Notes
PEGASUS® BT 4D GC×GC-TOFMS
Please complete the form to get access to all App Notes.
- Statistical Differentiation of Baijiu Spirits Using SPME-GC×GC-TOFMS and ChromaTOF® Tile Software
- Workflow for the Assessment of Key Aroma Compounds of Pumpernickel Bread Variations
- Comprehensive Evaluation of Scotch Whisky Aroma Profiles Using SPME-GC×GC-TOFMS
- Pesto Aroma Profile SPME
- Pesto ChromaTOF Tile SPME
- Frankincense and Myrrh: Visual Characterization and Comparison of Essential Oils
- Characterization of Citronella Essential Oil
- Characterization and Roast Level Differentiation of Coffee
- Differentiation of Honey Aroma Profiles
- Improved Characterization and Differentiation of Perfume Samples
- Differentiating Original-Brand and Imitation Perfumes with GCxGC-TOFMS and ChromaTOF Tile
eFoodLab Article | New Dimensions in Beverage Characterisation
In this issue, eFoodLab published an interview with Dr. Geraint (Taff) Morgan of the Applied Science & Technology Group at The Open University, UK, who discussed his team's activities as part of their impact agenda to develop and deploy novel analytical solutions for beverage products within the industry.
eFoodLab Article | Trends and Patterns in the Alcoholic Beverage Industry
eFoodLab spoke to some key players to investigate current trends and patterns of work in the sector and valuable insights were provided by "In The Welsh Wind", a distilled spirits company forging new and alternative approaches to produce authentic and sustainable Welsh Whiskey, "He Stringer Flavours", a flavour and fragrance company innovating flavour formulations to provide brands and consumers with increased choice and quality.
eFoodLab Article | Innovative Beer crafted from unsold bread
eFoodLab is talking about 'Cacciatori di Briciole' beer, exploring its aromatic intricacies through advanced gas chromatography techniques, a testament to sustainable brewing innovation.
Further Instrument Portfolio
Browse our line up of scientific analytical products sensory, flavor, and fragrance analysis to find the appropriate instrument for your specific purposes.
LECO's QuadJet™ SD is the ideal solution for samples which arrive in your lab. By combining the sensitivity of Flame Ionization Detection (FID) with the increased chromatographic resolution of comprehensive two-dimensional gas chromatography (GCxGC), the QuadJet SD delivers a better measure of the actual components of your sample than a straight GC analysis. No other system available on the market can deliver the same reduction in noise and error as the QuadJet SD.
Available exclusively from LECO, our L-PAL3 autosampler offers increased vial capacity, discrimination-free GC injections (ultrafast injections), an automatic tool exchange to switch between injector types (liquid, headspace, or SPME), minimized carryover, and the sensing of vial bottoms to avoid mis-injections.
The Easier Way To Make GC×GC Part Of Your Every-Day Analysis
Simply GC×GC from LECO is a free tool designed to walk you through the steps of creating an optimized GC×GC method for your complex samples. Create a GC×GC method from scratch, or convert an existing 1D method to GC×GC.
GC×GC Flow Modulator
Our innovative FLUX GC×GC flow modulator was designed with one goal in mind—to make GC×GC more routine, accessible, and easier for you.
Thermal modulation delivers the highest performance of any available modulator for GC×GC. Other types of thermal or valve-based modulators do not match up to the ruggedness, reliability, and performance of LECO's GC×GC modulator.
Ionization Source For Gas Chromatography Mass Spectrometry
The innovative Multi-Mode Source™ (MMS™) takes all of the advantages of the three most common ionization modes – Electron Ionization (EI), Positive Chemical Ionization (PCI), and Negative Chemical Ionization (NCI/ECNI) – and combines them into one easy-to-use source. No more hardware switching, no more alignment issues:
with the MMS, changing ionization modes is as easy as a click of a button.
Developed exclusively by LECO, ChromaTOF® is uniquely designed to meet the needs of today’s laboratory professionals by processing and analyzing the large amounts of data that are acquired with our time-of-flight instruments.
Developed exclusively by LECO, ChromaTOF® is uniquely designed to meet the needs of today’s laboratory professionals by processing and analyzing the large amounts of data that are acquired with our time-of-flight instruments.
Bring the Power of Accurate Mass and Confidence to your Identification Problems
LECO's Identification Grading System (IGS) eases data review by allowing users to quickly see, justify, have confidence in, and report on which chemicals are in a particular sample.
Let LECO help you find the right instruments for your needs.
If you want to learn more about our products and solutions for aroma analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
"I have used the LECO BT4D for the separation, identification, and quantification of anabolic steroids.
The advantages of the GC×GC system to separate stereoisomers in a complex matrix means time can be saved from doing complex sample preparation and extraction procedures. The ability to separate and quantify low levels of target analytes from high levels of matrix interferences has been key to my work. With LECO’s user-friendly ChromaTOF software, expert application scientists, and fantastic technical service team, LECO is a reliable and trusted research partner."
Mit 85 Jahren Erfahrung in der Labortechnik wissen wir inzwischen ziemlich gut, dass es nicht nur darauf ankommt, hochwertige, spezialisierte Technik anzubieten, sondern ebenso zuverlässige Lösungen, wenn es um individuelle Anforderungen wie Service, Wartung, Support und Know-How geht.
Lernen Sie unseren professionellen LECO Kundenservice kennen! Wir bieten Ihnen ein breites Leistungsportfolio und helfen Ihnen dabei, die Produktivität und Effizienz Ihres Labors zu steigern.
Überzeugen Sie sich selbst - was können wir für Sie tun?
LECO Solutions for MOSH/MOAH
Whatever your sample preparation workflow requirements are, harness the power of LECO GC×GC & TOF technology to solve the complex challenges of MOSH / MOAH Analysis.
LECO Solutions For Energy & Fuels Analysis
Expanding, conserving, and stretching our limited energy resources means that companies will need to be able to analyse new sources as well as validate the quality of existing supplies. LECO instruments enable energy companies to comply with increasingly stronger EPA regulations.
While LECO has continued to be a leader in carbon/sulfur testing of coal and coke, it has since expanded into biofuels, additives, diesel and petroleum products, and jet fuel. As these resources become more valuable, LECO technology is here to validate their potential and quality, while helping you meet government regulations.
Product portfolio
Tap into the power of cutting-edge technology. Our instruments excel in characterizing even the most intricate mixtures, enabling precise determination and ultimate analysis. Gain invaluable insights for e. g. calculating material/energy balances, optimizing efficiencies, and assessing emissions potentials. Experience the pinnacle of accuracy and efficiency in energy and fuels analysis with our advanced solutions.
Browse our line up of scientific analytical products for energy and fuels analysis to find the appropriate instrument for your specific purposes.
SC832 Sulfur/Carbon
LECO’s 832 Series of Elemental Determinators are specifically designed to perform carbon and sulfur analysis of coal, coke, lubricants, fuel oils, and many other organic and some inorganic materials. The 832 Series is a valuable resource for any laboratory needing fast and accurate analysis in solid fuels.
CHN828 Carbon/Hydrogen/Nitrogen Elemental Analysis
The CHN828 makes it possible to achieve fast results in organic matrices from food to fuels. The dual-stage furnace system operates at temperatures up to 1,050 °C with an exclusive oxygen environment ensuring the complete combustion of all organic samples, without requiring additional metal oxidizing reagents or other carrier gases. Macro sample mass capability paired with cycle times of 4 minutes make the CHN828 ideal for a diverse application base, while delivering unparalleled throughput.
TGA8O1 Moisture / Ash / Volatile Matter
The TGA801 is your total solution for fast and robust macro thermogravimetric constituent analysis. Determine weight loss as total moisture, ash, volatile content, or LOI in various organic, inorganic, and synthetic materials. The TGA801 is perfect for a variety of industries and applications – including feeds, milling products, foods, catalysts, coal/coke, and cement.
AC600 Semi-Automatic Calorimeter
The AC600 is an lsoperibol Calorimeter that provides fast and accurate calorific results for various organic materials such as coal, coke, fuel oils, and waste materials. lts unique design combines state-of-the-art hardware and software technology with automation and ergonomic features for improved instrument performance and throughput.
PEGASUS® BT GC-TOFMS
The tried-and-tested reliability and durability of our Pegasus brand in a convenient benchtop unit gives you more uptime, improved chemical data, and an increase in overall productivity and efficiency.
PEGASUS® BT 4D GC×GC-TOFMS
The tried-and-tested reliability and durability of our Pegasus brand in a convenient benchtop unit gives you more uptime, improved chemical data, and an increase in overall productivity and efficiency.
QuadJet™ SD
LECO's QuadJet™ SD is the ideal solution for samples which arrive in your lab. By combining the sensitivity of Flame Ionization Detection (FID) with the increased chromatographic resolution of comprehensive two-dimensional gas chromatography (GCxGC), the QuadJet SD delivers a better measure of the actual components of your sample than a straight GC analysis. No other system available on the market can deliver the same reduction in noise and error as the QuadJet SD.
PEGASUS® GC-HRT+ (High Resolution TOFMS)
High Resolution TOFMS technology provides high-performance MS capabilities, including acquisition speed, mass accuracy, accurate relative isotopic abundance, mass resolution, and dynamic range, all available simultaneously. Designed for the R&D lab to dive deep into petrochemical samples and solve complex matrices.
PEGASUS® GC-HRT+ 4D
LECO‘s Pegasus GC-HRT+ 4D provides users with the unprecedented ability to investigate the most complex petroleum samples and identify unknown analytes. Find more analytes than ever before using High Resolution Deconvolution® (HRD®) and comprehensive GC×GC chromatography.
Energy & Fuels Publication Library
Explore the depths of energy and fuels analysis with LECO. Dive into our informative eBook and discover a wealth of Application Notes covering mass spectrometry, thermal analysis, and elemental analysis in the field of energy and fuels. Gain valuable insights by filling out our form to access and download the eBook today.
eBook Energy & Fuels Applications
Interactive eBook for Energy & Fuels Applications
by LECO Europe B.V.
Please complete our form to download the eBook ...
Brochure LECO Solutions for Energy & Fuels Analysis"
LECO Brochure in A4 format for the “Energy & Fuels” market
by LECO Europe B.V.
Please download the Brochure ...
If you want to learn more about our products and solutions for energy & fuels analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Microplastics are a ubiquitous presence in the world, found from Arctic snow to Antarctic ice and everywhere in between. There are trillions of microplastic particles floating on surface water, and everyone from infants to adults are presumed to be ingesting anywhere from dozens to tens of thousands of these particles every day.
Now available as an on-demand video!
Watch LECO's Advanced MOSH / MOAH Analyser in action!
The first Time-of-Flight (TOF) mass spectrometer was proposed in 1946, and the design has been refined and iterated upon every since.
With an unlimited mass range visible in each spectrum and a high spectral generation speed, the advantages of TOF mass spectrometry were immediately clear. Though the instruments improved, they did eventually hit physical limitations that restricted the resolving power. More work had to be done.
All the tricks of the trade won't be enough if your instruments can't handle the speed. LECO's Pegasus® line is designed to take full advantage of the speed of TOFMS analyses without sacrificing the sensitivity you need, and our StayClean® Ion Source means you never have to slow down to clean out your engine.
Aberystwyth University
"We originally expected to purchase a quadrupole instrument so buying a TOF was a little unexpected but definitely worth it as the data is far richer than what a quadrupole would have supplied. In the three years we have had the instrument running metabolomic matrixes the source has never been cleaned and the data is still superb and consistent. We love our Pegasus BT, it does a fab job of running my FAME samples including milk, yogurt, kefir, biltong and bacteria."
CNAP | University of York
"Our metabolomics research has utilised a LECO Pegasus 4D for over 15 years. Total downtime has probably been less than 20 days for the entire 15 years. When we do have a problem or even a question about using the instrument, LECO are very swift to respond, resolve the issue and offer support and assistance usually within a day of contacting them, and quite often on the same day. The source has never been cleaned or replaced, and we still have the same detector from the original installation. Multiple papers have been produced using data produced from our LECO and I can honestly say it’s been a great asset to our team at York University."
University of Southampton
"In 2019 EPSRC funded our vision for a regional Centre of Excellence (CoE) in 2 dimensional gas chromatography and mass spectrometry. This Regional CoE, initially embracing the Universities of Bath, Portsmouth, Southampton, and Swansea, will significantly drive discovery, characterisation and quantification of new modalities, delivering a step change in capability for detection and identification of new species that cannot be separated and determined by 1D GC alone.
LECO’s Pegasus HRT 4D GC×GC-TOFMS and the benchtop BT4D GC×GC-TOFMS, both with extensive automated sample handling capability were delivered in late 2019 and early 2020. Installation of these state-of-the-art instruments was complicated by Covid-19 and lockdown 1.0. With such complex instrumentation, and application areas, effective training was key; here LECO took the initiative and provided both bespoke local and on-demand online training.
The level of service support and close collaborative relationship with LECO (applications team and account manager) has been first rate. Both systems can now be operated remotely, enabling high level users from across the South West region to access the instrumentation and allow many complex questions to be probed. Our work covers a vast array of application, e.g. petrochemical, environmental and metabolomics. The data sets are rich and complex, yet simplified by a user friendly software interface. Compared to 1D-GC, the 4D systems provide an astonishing number of additional analyte identifications, giving us deeper insight and understanding of the samples. Combining LECO’s high resolution mass spectrometry with comprehensive gas chromatography, multiple sample handling options such as SPME, Pyrolysis and TD along with full automation has created a world class laboratory of which we are all very proud."
The following presentations are available:
LECO Presentation At EURO Fed Lipid 2021
English Language
- "18th EURO Fed Lipid Congress an Expo, 21 October 2021"
Fundamentals on Comprehensive MOSH/MOAH Analysis
English Language
- "Fundamentals on LC-GC Coupling" by Dr. Andreas Bruchmann | Axel Semrau GmbH & Co KG
- "Principles and Instrumentation of GC×GC and ToF-MS" by Prof. Dr. Ir. Hans-Gerd Janssen | University of Wageningen & Unilever
- "LC–GC×GC–ToF-MS/FID: A Powerful Platform for MOSH&MOAH Determination" by Prof. Giorgia Purcaro | University of Liège
Spanish Language
- "Cromatografía Bidimensional Exhaustiva acoplada a Espectrometría de Masas de Tiempo de Vuelo: Características y viabilidad para el control y análisis alimentario" by Lourdes Ramos | CSIC- IQOG
- "Contaminación MOSH / MOAH. Verificación mediante GC×GC-TOF-MS" by Silvia Losa | SGS Berlín
Our latest online presentations for MOSH / MOAH Analysis are now available as an On-Demand session. With these fundamentals you will learn all the ins and outs on the LC–GC coupling, GC×GC and Time-of-Flight MS to be able to determine MOSH and MOAH in food products.
LECO Solutions for MOSH/MOAH
Whatever your sample preparation workflow requirements are, harness the power of LECO GC×GC & TOF technology to solve the complex challenges of MOSH / MOAH Analysis.
With these fundamentals you will learn all the ins and outs on the LC–GC coupling, GC×GC and Time-of-Flight MS to able to determine MOSH and MOAH in food products. Please register for our presentations.
The Multidimensional Chromatography Workshop draws experts in this exciting field to share and discuss their research. The informal workshop also provides an excellent opportunity for those interested in multidimensional chromatography to learn more about this unique analytical technique. Research topics include advancements in multidimensional chromatography technology and applications of this highly selective chromatographic approach.
The past year with the rise of Covid-19 around the Earth has been a challenge to all of us. See how our European subsidiaries dealt with the pandemic around Europe and how our customer support and other services adapted to these new situations in the different countries. Click on the countries to see our personal experiences!
If you need any further information about how LECO operates during the Corona pandemic or to schedule your personal appointment with us, click on the contact button.
The start of the years begins with the usual enthusiasm, targets set, goals to achieve and strategy to achieve them. I remember being in Dusseldorf for a managers meeting on March the 3rd. Life was still normal, and the word ’lockdown’ was only ever heard on a Friday when my children were watching Wrestling. We were able to travel, visit restaurants and have a beer without the constraints of the facemasks, social distancing and track and trace apps. Life was normal. Within a month the world changed – lockdowns, stay-at-home, work from home, stay safe.
As the LECO customers adapted to this new way of life due to COVID, so did we. Our sales force worked from home and like never before used this relatively unheard-of platform called Microsoft TEAMS to interact with customers.
“I hear the chimes of ‘TEAMS’
calling me in my sleep now.”
Our service team continued to work throughout the pandemic with the new additions to their LECO uniform. LECO face masks and gloves. And of course, let’s not forget the bottles of hand sanitiser. As well as remote selling was used, remote service support came to the forefront. Both sales and service teams adapted to continue the high level of support that has become a custom with LECO.
LECO UK has been able to adapt and continued to support our customers while keeping ourselves and customers safe. Let hope moving into 2021 we can get back to some sort of previous normality. The vaccines are coming and there is a glimmer of light at the end of the tunnel but for the moment we continue with the slogan of Hands – Face – Space.
Michael Reaney, UK Sales Director, LECO Instruments UK Ltd.
The first picture shows our engineer Yuri Laptev during a Pegasus 4D service visit to Skolkovo Institute of Science and Technology.
The second one was taken at the Analytika exhibition in Moscow last year.
Gulnara Shaidullina, Ph.D., Separation Science Sales Engineer, LECO Russia and CIS
It has for sure been a challenge even though Sweden have had less restrictions. When crossing borders to Norway, Denmark and Finland our service technicians have sometimes had to take Covid-19 tests before. We have been fortunate, no one in our team have been infected as we know of. We haven’t even been to Iceland since the start of the pandemic. Our service technicians try to go by their own cars to customers, which have meant drives up to 14 hours single way.
On the sales side it has of course been a challenge in other ways. But with ‘Teams’, online demos and Virtual Trade show our sales team have connected with our customers in the best way possible. We only attended one real trade show since the start of the pandemic – LabDays in Copenhagen – but the attendance was of course quite thin…
Lennart Schwartz, Ph.D, Sales Director Nordic Region, LECO Nordic AB
Since 14th of March of 2020, and the declaration of State of alarm in Spain, Leco Instrumentos started to work in a new different way, adapting to the new scenario of pandemic. All the employees completed a training course regarding the new risk at work and the personal protective equipment for COVID-19:
- We all learnt about the use of face masks and the way to wash our hands
- Some employees customised their masks… thanks to their mother’s support!
- Remote working was the only option in most of cases.
- Virtual meetings have come to stay.
- The service team has been active since the first day, working in safe conditions.
So far, everything was normal… But LECO Spain had to face a new challenge – to move to a new office. It was a hard task cleaning the old facilities and open boxes – a lot of boxes. And in times of COVID we had to consider to organise small groups at the office working together. Minimising risks was a priority despite of the fact that we needed to be operative in the new facility in a short time. The collaboration of the Tres Cantos-based employees was essential.
But the result made the effort worthwhile! And the Spanish LECO team is ready for 2021!
Leticia García, Commercial Director, Spain & Portugal
From the perspective of the German Service Centre, a Corona routine has emerged throughout the past months. Customer demands increased - ever so often our service engineers are only allowed to enter labs after presenting a negative Corona test result. Of course, this requires special logistics in scheduling. In addition, there are different Corona rules the federal states of Germany and abroad, which makes planning much more difficult. But our colleagues adapt, as the pictures show, and as our colleague Manuel Lindemann describes below.
"When the pandemic really took off from March / April 2020, I first noticed a lot of uncertainty among both myself and the customers. There were many questions: What is Corona? What happens if I fall ill? How will this affect my work? Will the customers still let me enter their lab? How will LECO react? Now, almost a year later, there are still some questions left to be answered, but as humans we adapt and get used to the new circumstances – positive and negative.
in the beginning of the pandemic, I remember waiting for hours in 100m-long queues between lorry drivers and other visitors at a company and having to wait for the gatekeeper to let me pass. And there were customers who had their "special" views. From "Corona doesn't exist” to “You don't need the mask here" and "We have an internal lockdown, you can't get in" – it was all there.
After one year many questions remain unanswered, but some questions have already become obsolete. What remained as well, unfortunately, are the waiting times at customers‘ sites. Simply walking in and working on a unit is no longer possible. "Where are you from? Have you had contact with infected people? What does your Corona Warn app say? Do you have any symptoms?” ...And so on. What I've also noticed is that social interaction often gets left behind these days unfortunately – be it a casual conversation or just a gesture that disappears behind the mask. But, hopefully that is to come back soon.
But LECO protect their employees very well and always has an open ear for questions – a solution will be found together. All in all, I think we have organised ourselves very well and will probably make it through the rest of the pandemic."
Manuel Lindemann & Thomas Post, LECO Instrumente GmbH Deutschland
After a beginning of year full of prospects and projects, the arrival of Covid-19 took us by surprise. Italy was the first European nation to be massively attacked by the virus, the first cases recorded were in the north of the country, particularly in Lombardy, the region where the headquarters of the LECO branch in Italy are located.
To counter the spread of the virus, the entire country was placed in the "red zone" and operations were greatly reduced to adapt to the new situation.
- The symposium of world interest on the GC×GC in Riva del Garda, as well as other local events, albeit no less important, have been cancelled
- We did our meetings online
- The office staff worked in smart working
- The technical staff continued to follow their customers both remotely via the telephone and with remote interventions, and in person with the help of masks, gloves, overalls and protective goggles.
The pandemic has led us to cover our faces with masks, but it has not managed to extinguish our enthusiasm and we hope that 2021, together with the vaccine, gives us the opportunity to resume showing our smiles.
Rita M. Monfredini, LECO Italy S.R.L.
We’re dealing with the pandemic problem in a similar way, like the rest of the world:
- Using, masks and gloves
- Struggling with scheduling sales visits
- Mostly using ‘Teams’ and mobile phones to contact with each other and with customers…
Tomasz Stójkowski, Sales Director LECO Poland & Baltics
Europe
Online Demo Service at European Application & Technology Center Berlin
Since February 2020 we provide an Online Demo Service at our European Application & Technology Center in Berlin, giving customers an insight into our LECO products and laboratory processes conveniently from their desks and without the need to travel. For our Online Demo Service, a good preparation is required to meet our's and our customers’ high standards.
Preparation
- The sales enigneer requests instrument, possible date, and time at the EATC
- After feedback, the date and time is clarified with the customer
- After completion of our internal Event Request Form to collect all needed information about the customer, instrument, date and time the EATC blocks the date for the customer
- The team at EATC provides an online meeting link accordingly and invites the sales engineer to this meeting
- The sales engineer then provides the invitation with this link to their customer and if needed other colleagues who will participate.
Demo Day
- Customer and sales engineer login to the online meeting which will be started by the EATC team.
- The camera at EATC is usually placed in front of the desired instrument, when the meeting starts.
- The sales engineer starts with an introduction of themselves and the EATC team in local language.
- This is followed by some introductory words to outline the demo – also in local language
- The EATC team can do measurements of standards, explain the analysis, and point and zoom the camera wherever needed to get the best possible instrument and software overview.
- It is also possible to measure customer samples, if they are provided some days in advance to the online demo.
Get in touch with us to arrange an individual online appointment for you!
Visit our LECO Virtual Trade Show
Due to the Corona pandemic, numerous trade shows and events are being cancelled or postponed where we would have liked to welcome or customers as a guest. To give you the opportunity to stay in touch with LECO, we have organised our LECO Virtual Trade Show. Our specialists invite you to get to know our solutions for various application fields and markets in a personal meeting.
Visit our registration website and book your free ticket today. Your local sales partner will schedule a meeting and guide you through our exhibition and introduce you to our solutions for your lab.
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It's that time of year again, when holiday songs play 24/7 on the radio and people start wondering what, exactly, frankincense and myrrh are and why they make good gifts. LECO placed these two oils in a Pegasus BT 4D to see the difference.
Frankincense (from the boswellia tree) and myrrh (from the commiphora tree) are both resins which are commonly used as perfumes and incense and have been for thousands of years. Essential oils extracted from these resins can be analyzed using gas chromatography, which is precisely what the scientists at LECO did.
By extending the analysis to a second dimension using the GC×GC analysis of the Pegasus BT 4D, even more information can be gleaned from the samples extracted from these substances. GC×GC analysis also inherently produces structured chromatograms where chemically similar analytes tend to elute in ordered bands through the GC×GC separation space. This provides context for identification and allows for rapid visual characterization of the compound classes.
For a more detailed breakdown of the analysis of these oils and how the GC×GC separation provides a huge advantage in the characterisation and comparison of these samples, fill in the form and check out our application note.
Watch the LECO’s webinar in cooperation with The Analytical Scientist now available for on-demand viewing. The webinar features "GC×GC-HR-TOFMS for untargeted screening of Breathomics" by Pierre-Hugues Stefanuto, Lead Scientist at University of Liège
Your Pegasus® BT is a powerful instrument, but if you're unsure how to use some of its features, you aren't able to get the full benefit from your investment. LECO is rolling out LECOLearn, an online, on-demand training site to help you maximise your laboratory.
Metabolomics presents challenges for both the analytical methods used and the data reduction required to interpret the results. No single analytical technique can be used for complete characterisation of the metabolome, and no metabolome has been completely characterised. However, GC-MS provides an established method to analyse the primary metabolome, whereas LC investigates the secondary and tertiary metabolites.
The rise of omics has been a hot topic in our group for the past few years – in part because our own expertise aligns somewhat with the needs of these fields. Metabolomics is then particularly challenging for the separation science community, demanding the application of high-end iterations of various techniques, including LC, GC, MS, and NMR. In fact, when it comes to metabolomics, most analytical tools have a “seat at the technique table” – after all, multimodality is the only way to make sense of such high sample complexity.
An Article by Pierre-Hugues Stefanuto, Delphine Zanella, and Jean-François Focant
How efficient is your workflow when it comes to food samples? Are you sure you're seeing everything your sample has to offer? Learn how LECO has been expanding what is possible when it comes to food safety analyses with this free series of webinars.
LECO hosted the LA2PC // Analytical Applications Poster Competition with the aim of improving our understanding and knowledge of LECO users’ work and research. This was a great opportunity to learn more from our users and introduce their work with LECO instruments to a wider base. LECO is proud that so many excellent posters were submitted. All entries are displayed in our poster gallery.
Dr. Ralf Löscher, Vice President of LECO Europe, talks to Thomas Gröger and Dr. Jürgen Schnelle-Kreis from the Helmholtz Zentrum München – the German Research Center for Environmental Health to learn about the impact of aerosols on our everyday life and health and gain some background information on their work.
We are proud to announce the successful delivery and installation of a unique apparatus set at our unique customer. NOFER INSTITUTE OF OCCUPATIONAL MEDICINE in Łódź, which includes the BIOLOGICAL MONITORING AND ENVIRONMENT DEPARTMENT, headed by Prof. Dr. hab. n. med. Wojciech Wąsowicz is a thriving and opinion-forming center, participating in many national and international programs.
How efficient is your workflow when it comes to food samples? Are you sure you're seeing everything your sample has to offer? Learn how LECO has been expanding what is possible when it comes to food safety analyses with this free series of webinars.
All our webinars will be approximately 30 minutes long with a Q&A session at the ends. Register for any or all that interest you!
Or visit our New Virtual Trade Show
Please join us for two upcoming eSeminars on SepScience.com. We present how state of the art LECO GC-TOF-MS and GC×GC-TOF-MS technologies can dramatically enhance your applications for Food Analysis (9th June) and Environmental (11th June).
Click to register now!
Today, 20th May, is UN World Honey Bee Day. The honey bee is an important pollinator species that contributes an estimated $15 billion a year to the US economy through crop pollination and £690 million to the UK economy. Honey bees are also important wild pollinators, and play a key role in maintaining biodiversity and ecosystem services in many ecosystems.
At LECO’S GC×GC Workshop & Symposium (filmed at the LECO European Application and Training Centre, Berlin, Germany) Paul Harvath gave a talk entitled "Evaluation of Oxidized Base Oils by Flow Modulated Two-Dimensional Gas Chromatography – Time of Flight Mass Spectrometry". In his talk he gave an insight about the history and future of engine oils for cars, and how the lubricants changed over the times.
Department of Pharmacy, University of Naples Federico II
"I have been using a GC-TOFMS Pegasus BT since January 2018 for Metabolomics projects. I have mainly analysed murine tissues extracts, and, I'm very happy about its robustness and high sensitivity."
UMR QualiSud, University of Avignon, France
"I use a LECO mass spectrometer for plant metabolomics ; it is an efficient machine with a very low detection limit and the Chromatof deconvolution algorithm allows to find hundreds of compounds in complex extracts."
Faculty of Forestry and Wood Sciences, Czech University of Life Sciences Prague, Czech Republic
"I have been working with LECO instruments for approx. ten years. I worked with the PEGASUS® 4D, TruTOF, GC-HRT and, for few days in Berlin, with the Pegasus BT and BT 4D – I really enjoyed that. There are several reasons why I like working with the devices and why I would not consider using other GC-MS insturments.
- LECO instruments are reliable and robust with well working peak find and mass spectral deconvolution algorithms.
- In principle, LECO instruments are allowing both target and non target analysis which can be performed in one run, with nice sensitivity.
- Data processing is easy and everything is done in one SW – no need to use complicated combinations of SWs.
- LECO has an excellent customers support"
Wolfson Atmospheric Chemistry Laboratories, University of York
"Following years of service from the old LECO PEGASUS® 4D TOF GC-MS, we upgraded to a new LECO Pegasus BT4D TOF GC-MS. The decision was made due to the exceptional separating power afforded by thecryogenic modulation and the durability of the LECO StayClean® sourcetechnology which has been carried into the updated system. The combination of the two open up a wide variety of analyses to us whichenable use of this instrument in many aspects of our research."
National Centre for AtmosphericScience (NCAS), University of York
"We send instruments into the harshest of environments and run very demanding samples on them. Bearing this in mind, our decision to upgrade the GC-MS at our remote Cape-Verde site to the new LECO PEGASUS® BT was driven by the promise of the StayClean® source. This minimizes down time and eliminates operations which are difficult to carry out when working with remote systems. The increased sensitivity of theinstrument enables us to take smaller sample volumes which again assists with easing the burden placedon the analytical machine. Finally! the upgrade from quadrupole to time of flight mass spec will enable us to keep historical datasets which can be interrogated for any compounds which prove interesting in the future."
Department of Civil Engineering University of Strathclyde
"In 2013, I became responsible for overseeing the department’s analytical suite which included a LECO PEGASUS® 4D GC×GC TOF MS as our flagshipinstrument. I had no experience in gas chromatography and found even a standard GCMS daunting. Over the past years, I received extensive support from LECO. Especially withsupport from LECO UK the instrument is still running strong a decade after purchase. I anticipate it will go for another decade and then some."
ALS Enviromental, United Kingdom
"I believe this technology and methodology will profoundly change water analysis realising major benefits for both laboratories and their customers."
SGS Institut Fresenius GmbH Berlin, Germany
"We at SGS MOSH/MOAH group are using the GC × GC-TOFMS from LECO to separate the highly complex fractions of MOSH/MOAH contaminates in food. When you want to identify special patterns of contamination species amongst other analytics (e. g carotenoids) you need a high separation power in combination with a fast screening MS. This is provided by the LECO TOF. Actually we have a new project together with LECO and another company to quantify MOSH/MOAH fractions. The complexity of the instrumentation is high, but with the support of the application team from LECO we reach our goals."
Environment Reference Lab, APA – Agência Portuguesa do Ambiente
"Initially we had some fears about whether the option of the time of flight detector would be the best for our laboratory, since we have no other system of this kind installed. However, at the end of 6 months of operation with the GC-TOFMS system, it was widely recognized internally that we made the right choice. An easy-to-operate system with high sensitivity, reproducibility and severalanalysis options for a large universe of analytes, and in the most varied matrices increases the versatility of laboratory operation as well as the possibility of responding to the most demanding customer requests."
Centre for Molecular and Cell Technologies, Saint Petersburg State University Research Park
- Analytical Phytochemistry Laboratory // Komarov Botanical Institute
- Department of Plant Physiology and Biochemistry // Saint Petersburg State University
- Department of Plant Biochemistry and Molecular Biology // Vavilov Research Institute of Plant Industry
"Our virtual metabolomics research center has six GC-MS instruments, and the LECO PEGASUS® 4D is the crown jewel of our science park. The results of GC-MS profiling performed using GC×GC technologies has madea strong impression on users and has seriously improved the quality of ourpublications. The fast-scanning capabilities of the TOF-analyzer effectively augment the dataobtained on the ordinary quadrupole, especially when working with the most complexmatrices which are most often the subject of metabolomics analysis. The reliability of the device is especially deserving of praise. The equipment can withstand a very demanding load with constant, round-the-clock operation."
Università degli Studi del Piemonte Orientale, Italy
"With the Pegasus BT 4D performing untargeted analysis today is very easy, thanks to the high sensitivity of the instrument, we are able to mine and analyze any type of sample! A combination of very good sensitivity, quality to price ratio and high flexibility make the Pegasus BT 4D system perfect for analysis of every sample"
University of Naples, Italy
"Pegasus BT is the perfect choice for identifying well-known metabolites at low concentration level in our sample, and also discovering new compounds. The most surprising advantage of the BT system is the ion source robustness! We usually work with dirty and complex samples, but we have never observed drop of sensitivity during our analyses.This reduces the time and cost of our analyses!"
TURKU Metabolomics Facility, Finland
"We use the LECO Pegasus BT instrument for the quantification of small polar metabolites. We developed a hybrid method where we quantitate 51 metabolites with standard curves and screen for any other small polar metabolites in a wide range of biological samples. This assay has a great dynamic range thanks to the sensitivity of the BT. The StayClean® ion source allows us to run hundreds of samples in a batch and be confident that the ion source will remain clean even with dirty samples such as plasma."
Czech Academy of Science, Tschechische Republik
"Compared to GC equipped with a single column, the Pegasus 4D enabled me to separate unbelievable number of analytes! Tens of thousands of separated peaks in one run was not an exception. But where the separation was not perfect, ChromaTOF software and its deconvolution algorithm did the job. Such excellent ‘separating power’ helped me discover new types of plant PCB metabolites."
Helmholtz Zentrum München (HMGU) Department “Comprehensive Molecular Analytics“, Germany
"This combination of ultrahigh chromatographic separation with high mass resolution might be still unique for a commercial available end user system."
Our new eBook summarises a large part of LECO’s application work in the field of food testing. In addition to the Application Compendium, the eBook includes an introduction to GC×GC- and TOFMS-technology, followed by an overview of the different hardware and software solutions that were used for the food testing applications. A bibliography with additional references can be found in the appendix.
The eBook is downloadable at SeparationScience now.
Download the eBook here…
NEW Online Demo Service at our European Application and Technology Center in Berlin
We can now present our instruments and application solutions to you ONLINE, enabling you to gain insight into how LECO products could enhance your laboratory processes and results!
Visit us conveniently from your desk and without the need to travel. Our new ONLINE DEMO SERVICE allows you see product introductions and receive tips and tricks from our experts.
Would you like to know how we can help your sample analyses?
Just let us know and we can arrange a demo!
Contact your local sales team for an individual online appointment.
As laws and regulations change, cannabis and all it’s related chemical compounds of interest are showing up in a wide variety of consumer products. LECO instruments, that combine powerful Time-of-Flight Mass Spectrometry (TOF-MS) and Comprehensive Two Dimensional Gas Chromatography (GC×GC) technologies, can make your analyses more efficient. Find out here, how to save time and money by quantifying and identifying both the terpene and cannabinoids in just one injection. The same injection can even reveal the presence of pesticides and more!
How can we do this? Using GC×GC drastically increases analyte separation, which together with high quality full mass range spectra obtained by TOF-MS, enables powerful deconvolution analyte finding using ChromaTOF.
Do you want to learn more about "Determining Terpene Profiles of Cannabis Strains", then watch the presentation of Joe Binkley, Director - Separation Science Applications.
At LECO’S GC×GC Workshop & Symposium, Dr. Diane Turner gave a talk about "Selectivity: Wann, wo und wie man sie nutzt“ The talk covers techniques for sample analysis, selectivity in choosing the right technical setup (column choice, inlet parameters etc.), and also data analysis optimisation.
Meeting of the London Metabolomics Network and South East Region Analytical Division of the Royal Society of Chemistry at Burlington House, London
Alan Griffiths speaks about the top of the range technique for GC×GC Separation provided by LECO. The video has been recorded at the meeting of the London Metabolomics Network and South East Region Analytical Division of the Royal Society of Chemistry at Burlington House, London. The video will be uploaded to SepScience.com for our recent PEGASUS® campaign.
Fireworks are a staple of America’s Independence Day celebrations. It is estimated that 16,000 fireworks displays are held in the United States each year and American consumers will spend more than $1 billion in firework sales to mark the holiday! Beyond a big bang and bright lights, how do these fireworks affect the environmental world around them? LECO’s world headquarters are located in Saint Joseph, Michigan, a beach town on Lake Michigan where fireworks are a prominent backdrop to the 4th of July celebration. Last summer, our applications lab thought it would be a worthwhile and interesting experiment to test the water surrounding the firework launch spot to explore if there were any short-term environmental impacts. The influx of tourists to the Lake Michigan beaches during the holiday is sure to contribute chemicals from personal care products (sunscreen and insect repellent) to the water as well. Evaluating these potential contaminants surrounding the July 4th holiday was the objective of this study.
The analysis was conducted by taking water samples from three different places along the shoreline; the fireworks launch location off the pier, as well as two local beaches close to the launch site. This was done on July 2nd as well as on July 4th (an hour after the fireworks show) to provide an accurate measurement. LECO’s Pegasus HRT+ 4D system was used to analyse the water samples, which offers comprehensive two-dimensional gas chromatography coupled to high-resolution time-of-flight mass spectrometry (GC×GC-HRTOFMS). GC×GC-HRTOFMS proved a powerful tool for exploration as it provided a full non-targeted analysis of the water samples before and after the fireworks show, clearly demonstrating the chemical differences between the two. GC×GC-HRTOFMS was also able to pinpoint contributions to the environmental pollution that occurred as a result of these pyrotechnic displays and the increased human traffic near the water sampling sites.
So what happened to the water quality of Lake Michigan from the increased tourism and fireworks? The results may surprise you…
Non-targeted analysis, data science and innovation have synchronised to underpin the next generation of separation science analysis in mass spectrometry. LECO UK’s separations science product specialist Alan Griffiths explains.
“Ideas often spark one another, and chain reactions occur. As with chemical reactions, ideas can remain contained in relatively small areas before gradually spreading outward. California’s Silicon Valley is a focal point for technology. For mass spectrometry (MS), the UK’s city of Manchester is a focal point. Manchester is where the first commercial mass spectrometer built outside of the US was produced…“
Chemistry World // Issue 12/2019 // Article by Alan Griffiths
Ralf Löscher speaks about the latest technologies, as well as many years experience LECO has in the field of TOFMS instrumentation. The special focus of this interview refers to the food industry and the special benefits LECO offers to this market.
“In the field of chromatographic separation science technology, LECO offers GC coupled to time-of-flight (TOF) mass spectrometry (MS). This includes one-dimensional as well as two-dimensional chromatography (GC×GC), which increases chromatographic resolution and sensitivity. In addition, our latest technology is competitively priced in relation to triple quadrupole alternatives. Furthermore, GC-TOF-MS technology is basically unbeatable for the analysis of residues in complex matrices such as teas, spices, oily products, but also baby food.“
eFoodLab // Issue 02/2019 // Interview with Ralf Löscher
Congratulations to the winner of LECO UK’s first poster competition Rachel Hand of De Montfort University / The Open University and also to our runner-up Sonia García Alcega of The Open University.
Frank Dorman, an Associate Professor of Biochemistry and Molecular Biology at Penn State University, spoke at our ASMS breakfast seminar about his experience using our Pegasus BT 4D benchtop GC×GC-TOFMS to analyze environmental contamination in the Susquehanna river.
LECO’s PEGASUS® GC-HRT+ 4D will be the newest addition to the University of Southampton’s School of Chemistry, offering unique capabilities to UK researchers. Read what Professor John Langley has to say about the new mass spectrometer. “Highly advanced Southampton spectrometer to spearhead chemical research across southern region. Researchers across the south of England will analyse novel and strategically important chemistries through a new mass spectrometer at the University of Southampton.“
Interesting talks, excellent speakers, great conversations and discussions, stunning food and an amazing venue all lead to a great LS3UK in Manchester on 29 – 30 October.
LECO invites you to a diverse Metabolomics Analysis event at the EATC in Berlin. Expert speakers will present how the use of LECO GC-TOF-MS and GC×GC-TOF-MS enhances their latest target and untargeted metabolomics analysis applications in various fields such as Human disease, foodomics and plant biomarkers. These lectures will be supplemented with a laboratory session showcasing the latest LECO instrumentation and software. The participation is free of charge, including a special evening event on 27th November!