Displaying items by tag: TOFMS

Microplastics: Seeing the Details with GC×GC

Microplastics: Seeing the Details with GC×GC

Microplastics are a ubiquitous presence in the world, found from Arctic snow to Antarctic ice and everywhere in between. There are trillions of microplastic particles floating on surface water, and everyone from infants to adults are presumed to be ingesting anywhere from dozens to tens of thousands of these particles every day.

Folded Flight Path®: Ten Years of High Resolution

Folded Flight Path®: Ten Years of High Resolution

The first Time-of-Flight (TOF) mass spectrometer was proposed in 1946, and the design has been refined and iterated upon every since.
With an unlimited mass range visible in each spectrum and a high spectral generation speed, the advantages of TOF mass spectrometry were immediately clear. Though the instruments improved, they did eventually hit physical limitations that restricted the resolving power. More work had to be done.

Pegasus GC-HRT | Enhancing of a Powerful Discovery Tool with a Novel Multi-Mode Ion Source

Pegasus BT 4D | Differentiation of Regular and Barrel-Aged Maple Syrups with ChromaTOF® Tile™

Pegasus BT 4D | Determining Terpene Profiles of Cannabis Strains Using GC and GCxGC with High Performance TOFMS

Pegasus BT 4D | Determination of Pesticides in Tomato by GCxGC-TOFMS

Competence Days | Fundamentals on Comprehensive MOSH/MOAH Analysis

Webinar Fundamentals on Comprehensive MOSH-MOAH Analysis

With these fundamentals you will learn all the ins and outs on the LC–GC coupling, GC×GC and Time-of-Flight MS to able to determine MOSH and MOAH in food products. Please register for our presentations.

"The Ultimate Untargeted Technique" – LECO in colaboration with the Analytical Scientist

The rise of omics has been a hot topic in our group for the past few years – in part because our own expertise aligns somewhat with the needs of these fields. Metabolomics is then particularly challenging for the separation science community, demanding the application of high-end iterations of various techniques, including LC, GC, MS, and NMR. In fact, when it comes to metabolomics, most analytical tools have a “seat at the technique table” – after all, multimodality is the only way to make sense of such high sample complexity.

An Article by Pierre-Hugues Stefanuto, Delphine Zanella, and Jean-François Focant

“Breath Biomarkers of Infection” in the Analytical Scientist

From cancer to diabetes to the recent rise of COVID-19, we will all likely come face-to-face with a threat to our health. Contemporary medicine has ever-improving tools to identify and combat diseases, but there are gaps – in speed, in invasiveness, in coverage, in access, and in accuracy. Can we do better? And how can we ensure that new approaches provide the same level of diagnostic potential as those currently in service?

Jane Hill, Associate Professor of Engineering, and Billy Boyle, CEO of Owlstone Medical, explain how their research in the area of breath analysis is opening new diagnostic doors.

"Determination of Pesticides in Tomato Products by GC×GC-TOFMS" – LECO in colaboration with Separation Science

Find out how the use of Comprehensive Two-Dimensional Gas Chromatography (GC×GC) with Time-of-Flight Mass Spectrometry (TOF-MS) demonstrates excellent matrix-analyte and analyte-analyte separation quality of a high number of target pesticides, at high sensitivity.

The LECO Pegasus BT 4D was used to develop a robust and straightforward quantification workflow adhering to SANTE requirements.

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Pegasus 4D | Detection of Sulfur-Containing Metabolites of Asparagus in Urine

Pegasus BT 4D | Quantitation and Non-Target Detection of Pesticides in Spinach Extract

SeparationScience featuring LECO Food Testing Applications e-Book

Our new eBook summarises a large part of LECO’s application work in the field of food testing. In addition to the Application Compendium, the eBook includes an introduction to GC×GC- and TOFMS-technology, followed by an overview of the different hardware and software solutions that were used for the food testing applications. A bibliography with additional references can be found in the appendix.

The eBook is downloadable at SeparationScience now.
Download the eBook here… 

Pegasus 4D | GC-TOFMS and GC×GC-TOFMS of Organophosphate Pesticides in Ash Leaves

Pegasus 4D | Analysis of Pesticides by GC×GC-TOFMS Using a Consumable-Free Modulator

Pegasus 4D | Analysis of Pesticides in Brewed Green Tea by SBSE-GC×GC-TOFMS Showing Baseline Resolution of Three Pesticides in the 2 Dimension Separation

Pegasus 4D | Analysis of Pesticides in Edible Oils by GC×GC–TOFMS

Pegasus 4D | Determination of 287 Pesticides at Trace Levels by GC×GC–TOFMS

Pegasus 4D | Analysis of Multiple Classes of Cigarette Smoke Constituents by GC×GC-TOFMS

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Pegasus 4D | Analysis of Sagebrush Aromas by Headspace SPME-GC×GC-TOFMS and Utilization of Variable Modulation in the Second Dimension Separation

Pegasus HT | Analysis of Pesticide Residues in Citrus Oils by GC×GC-TOFMS with Minimal Sample Preparation

Pegasus HT | Screening and Quantitation of Pesticides in Jonagold Apples by Comprehensive Two-Dimensional Gas Chromatography – Time-of-Flight Mass Spectrometry (GC×GC-TOFMS)

Pegasus HT | GC×GC Separation of the Pesticides Beta-Hexachlorocyclohexane and Trifluralin

Pegasus HT | Analysis of PAHs in Infant Formula and Blueberries Using QuEChERS and GC×GC-TOFMS

Pegasus HT | SBSE-GC×GC-TOFMS Trace Level Organochlorine and Organophosphorous Pesticides Analysis in Brewed Green Tea

Pegasus HT | Analysis of 3-MCPD Esters in Edible Oils Using Large Volume Injection Coupled to Comprehensive Gas Chromatography – Time-of-Flight Mass Spectrometry

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Pegasus GC-HRT | Analysis of Polychlorinated Biphenyls (PCBs) in Fish Oil Supplements by Gas Chromatography with High Performance-Time of Flight Mass Spectrometry

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e-Food Lab International // Interview with Ralf Löscher

Ralf Löscher speaks about the latest technologies, as well as many years experience LECO has in the field of TOFMS instrumentation. The special focus of this interview refers to the food industry and the special benefits LECO offers to this market.

“In the field of chromatographic separation science technology, LECO offers GC coupled to time-of-flight (TOF) mass spectrometry (MS). This includes one-dimensional as well as two-dimensional chromatography (GC×GC), which increases chromatographic resolution and sensitivity. In addition, our latest technology is competitively priced in relation to triple quadrupole alternatives. Furthermore, GC-TOF-MS technology is basically unbeatable for the analysis of residues in complex matrices such as teas, spices, oily products, but also baby food.“

READ MORE…

eFoodLab // Issue 02/2019 // Interview with Ralf Löscher

 

Pegasus HT | Quantification of Contact Allergens in Personal Care Products with GC and Full Mass Range TOFMS

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